Pregnancy as foreground in cystic fibrosis carrier testing decisions in primary care.
Pregnancy as foreground in cystic fibrosis carrier testing decisions in primary care.
复制标题
怀孕作为初级保健中囊性纤维化携带者检测决策的前景。
DOI：
10.1089/gtmb.2008.0085
复制
发表时间：
2009
影响因子：
1.4
通讯作者：
Williams,JanetK
中科院分区：
文献类型：
--
作者：
Sparbel,KathleenJH;Williams,JanetK
囊性纤维化携带者检测（CFCT）是初级保健机构提供的首批产前DNA检测之一。本文从一项描述性定性研究描述了怀孕对妇女接受社区产前护理的CFCT决策的影响。在美国中西部初级保健诊所接受产前护理的27名妇女完成了半结构化访谈。访谈录音采用内容分析法进行分析。参与者从“怀孕”的角度描述了决策的影响和策略。态度和信念的模式包括(1)处理情绪，(2)怀孕是自然的，(3)考虑孩子。决策过程中的策略包括(1)减轻压力，(2)选择相关的，(3)做正确的事，(4)做好准备，(5)延迟信息，(6)信靠上帝。虽然一些妇女提到了其他因素，但主要主题反映了目前怀孕对决策过程的影响。这些发现表明，怀孕对决策过程有很大的影响，可能不是就基因携带者检测做出充分知情决定的最佳时机。需要进一步了解影响基因检测决策过程的因素。提倡在受孕前提供CFCT。
Cystic fibrosis carrier testing (CFCT) is among the first of the DNA tests offered prenatally in primary care settings. This paper from a descriptive qualitative study describes the influence of pregnancy in CFCT decisions by women receiving community-based prenatal care. Twenty-seven women receiving prenatal care in Midwestern U.S. primary care clinics completed semistructured interviews. Audiotaped interviews were analyzed using content analysis. Participants described decision-making influences and strategies from the perspective of “being pregnant.” Patterns of attitudes and beliefs include (1) dealing with emotions, (2) pregnancy is natural, and (3) thinking about the baby. Strategies in the decision-making process included (1) reducing stress, (2) choosing what is relevant, (3) doing everything right, (4) wanting to be prepared, (5) delaying information, and (6) trusting God. While other factors were mentioned by some women, major themes reflect the influence of currently being pregnant on the decision-making process. These findings suggest that pregnancy is a powerful influence on the decision-making process and may not be the optimal time to make fully informed decisions regarding genetic carrier testing. Further understanding of factors influencing the genetic testing decision-making process is needed. Offering CFCT prior to conception is advocated.