MOVING THE RETINA - CHOROIDAL MODULATION OF REFRACTIVE STATE
MOVING THE RETINA - CHOROIDAL MODULATION OF REFRACTIVE STATE
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DOI：
10.1016/0042-6989(94)e0049-q
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发表时间：
1995-01-01
期刊：
影响因子：
1.8
通讯作者：
CHRISTENSEN, AM
中科院分区：
文献类型：
--
作者：
WALLMAN, J;WILDSOET, C;CHRISTENSEN, AM
鸡眼能够通过向前推视网膜或向后拉视网膜来改变其屈光状态多达7 D;这受到脉络膜、视网膜后面的血管组织和色素上皮的厚度变化的影响。小鸡的眼睛首先通过戴扩散器近视，然后允许不受限制的视觉发展脉络膜厚几倍于正常的几天内，从而加快从剥夺性近视恢复。脉络膜扩张不会发生时，视觉线索减少，在不受限制的视觉照明期间。此外，在通过眼镜片呈现近视或远视散焦的鸡眼中，脉络膜分别扩张或变薄，以补偿所施加的特定散焦。因此，当晶状体被移除时，眼睛突然发现其折射误差具有相反的符号，并且脉络膜厚度再次通过在相反方向上改变来补偿。如果眼睛的局部区域通过部分漫射器变得近视，然后给予不受限制的视觉，脉络膜仅在近视区域中扩张。虽然脉络膜扩张的机制是未知的，它可能涉及增加路由的房水到葡萄膜巩膜流出或血管生成的水运动到脉络膜。后者是兼容的增加脉络膜蛋白聚糖合成时，眼睛戴积极的镜头或后，扩散删除。
The chick eye is able to change its refractive state by as much as 7 D by pushing the retina forward or pulling it back; this is effected by changes in the thickness of the choroid, the vascular tissue behind the retina and pigment epithelium. Chick eyes first made myopic by wearing diffusers and then permitted unrestricted vision developed choroids several times thicker than normal within days, thereby speeding recovery from deprivation myopia. Choroidal expansion does not occur when visual cues are reduced by dim illumination during the period of unrestricted vision. Furthermore, in chick eyes presented with myopic or hyperopic defocus by means of spectacle lenses, the choroid expands or thins, respectively, in compensation for the specific defocus imposed. Consequently, when the lenses are removed, the eye finds its refractive error suddenly of opposite sign, and the choroidal thickness again compensates by changing in the opposite direction. If a local region of the eye is made myopic by a partial diffuser and then given unrestricted vision, the choroid expands only in the myopic region. Although the mechanism of choroidal expansion is unknown, it might involve either a increased routing of aqueous humor into the uveoscleral outflow or osmotically generated water movement into the choroid. The latter is compatible with the increased choroidal proteoglycan synthesis either when eyes wear positive lenses or after diffuser removal.