Distraction of the frontal bone outside the cranial plane: a rabbit model.
Distraction of the frontal bone outside the cranial plane: a rabbit model.
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DOI：
10.1097/00001665-199307000-00013
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发表时间：
1993-07-01
期刊：
影响因子：
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通讯作者：
Argamaso, R V
中科院分区：
文献类型：
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作者：
Barone, C M;Ferder, M;Argamaso, R V
使用 Ilizarov 原理对 17 只 22 周大的新西兰白兔进行颅平面外额骨牵引。 5只兔子仅进行额骨截骨术，属于对照组； 5只兔子为假手术对照组，进行额骨截骨加定制头套矫治器的应用；实验组7只家兔，进行额骨截骨术，应用头带牵引。额骨每隔一天升高1毫米，持续8周，然后处死动物。术前和 8 周结束时均进行头影测量。还对头骨进行了组织学检查。与假手术对照组相比，实验组的额骨显着升高（p < 0.05）。僵硬的骨头填充了分心的部分，将额骨与颅骨平面结合在一起。因此，使用这种兔子模型可以通过牵引成骨来推进额骨。
Distraction of the frontal bone outside the cranial plane using the Ilizarov principle was performed in 17 22-week-old New Zealand white rabbits. Five rabbits had frontal bone osteotomy only and were in the control group; 5 rabbits were placed in the sham control group and had frontal bone osteotomy plus application of a customized headgear appliance; and 7 rabbits were placed in the experimental group, which underwent frontal bone osteotomy application of the headgear and distraction. The frontal bone was elevated 1 mm every other day for a period of 8 weeks, and the animals were then killed. Cephalometry was performed both preoperatively and at the end of the 8-week period. Histological examination of the skulls was also performed. The experimental group showed a significantly elevated frontal bone compared to the sham control group (p < 0.05). Callous bone filled the distracted segment, which united the frontal bone with the cranial plane. Therefore, frontal bone advancement by distraction osteogenesis is possible using this rabbit model.