Central vein catheter-related thrombosis in intensive care patients - Incidence, risks factors, and relationship with catheter-related sepsis
Central vein catheter-related thrombosis in intensive care patients - Incidence, risks factors, and relationship with catheter-related sepsis
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DOI：
10.1378/chest.114.1.207
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发表时间：
1998-07-01
期刊：
影响因子：
9.6
通讯作者：
Carlet, J
中科院分区：
文献类型：
--
作者：
Timsit, JF;Farkas, JC;Carlet, J
目的：评估 ICU 患者导管相关中央静脉血栓形成的发生率和危险因素。设计：观察性前瞻性多中心研究。设置：8 个床位的外科 ICU、10 个床位的心血管外科 ICU 和 10 个床位的内外科 ICU。患者：在 18 个月期间，纳入了 265 个颈内或锁骨下导管。通过在 64 年前或 64 年前进行的双重扫描探查静脉（RR，2.44；95% CI，2.05 至 3.19）与导管相关血栓形成独立相关。而且，发生血栓时，发生导管相关性脓毒症的风险是其2.62倍（p=0.011）。结论：导管相关性中心静脉血栓是ICU患者中心静脉置管常见的并发症，与导管相关性脓毒症密切相关。
Objective: To evaluate the incidence and risk factors for catheter-related central vein thrombosis in ICU patients.Design: Observational prospective multicenter study.Setting: An 8-bed surgical ICU, a 10-bed surgical cardiovascular ICU, and a 10-bed medical-surgical ICU.Patients: During an 18-month period, 265 internal jugular or subclavian catheters were included. Veins were explored by duplex scanning performed just before or 64 years (RR, 2.44; 95% CI, 2.05 to 3.19) were independently associated with catheter-related thrombosis. Moreover, the risk of catheter-related sepsis was 2.62-fold higher when thrombosis occurred (p=0.011).Conclusions: Catheter-related central vein thrombosis is a frequent complication of central venous catheterization in ICU patients and is closely associated with catheter-related sepsis.