Ovarian cancer and the immune system.

Ovarian cancer and the immune system.
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卵巢癌和免疫系统。

DOI:
10.1016/j.gore.2017.01.002
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发表时间:
2017-02
影响因子:
1.2
通讯作者:
Coosemans A
Coosemans A
中科院分区:
其他
文献类型:
--
作者:
Baert T;Vergote I;Coosemans A

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针对Turner等人在《妇科肿瘤学》上发表的题为“卵巢癌和免疫系统-靶向治疗的作用”的综述进行的简短交流。我们认为,全身免疫参数可能是一个很好的替代肿瘤活检,以了解卵巢癌的免疫学背景。免疫系统是卵巢癌行为的重要参与者。免疫系统的肿瘤内研究显示压倒性的免疫抑制。血液中的免疫特征作为一种新的生物标志物可能很重要。
Short communication in response to the review of Turner et al. entitled “Ovarian cancer and the immune system - the role of targeted therapies” published in Gynecological Oncology. We believe systemic immune parameters might be a good alternative to tumor biopsy to gain insight in the immunological background of ovarian cancer. The immune system is an important player in ovarian cancer behaviour. Intratumoral studies of the immune system show an overwhelming immunosuppression. The immune signature in the blood can be important as a new biomarker.