Antimicrobial activity of reuterin in combination with nisin against food-borne pathogens
Antimicrobial activity of reuterin in combination with nisin against food-borne pathogens
复制标题
DOI：
10.1016/j.ijfoodmicro.2004.03.009
复制
发表时间：
2004-09-01
影响因子：
5.4
通讯作者：
Medina, M
中科院分区：
文献类型：
--
作者：
Arqués, JL;Fernández, J;Medina, M
研究了reuterin单独或与nisin联合对牛奶中不同食源性革兰氏阳性和革兰氏阴性致病菌的抑菌活性。Reuterin （8 AU/ml）对单核增生李斯特菌表现出抑菌活性，对金黄色葡萄球菌在37℃时表现出轻微的杀菌活性。对大肠杆菌O157:H7、霍乱沙门氏菌亚种均有较高的抑菌活性。猪霍乱菌，小肠结肠炎耶尔森菌，嗜水气单胞菌亚种。亲水菌和空肠弯曲杆菌。reuterin与nisin （100 IU/ml）联用，37℃作用24 h后对单核增生乳杆菌有明显的协同作用，对金黄色葡萄球菌有轻微的加性作用。reuterin与nisin联合使用对革兰氏阴性病原菌的抑菌作用没有增强。(C) 2004 Elsevier B.V.版权所有
Antimicrobial activity of reuterin individually or in combination with nisin against different food-borne Gram-positive and Gram-negative pathogens in milk was investigated. Reuterin (8 AU/ml) exhibited bacteriostatic activity against Listeria monocytogenes, whereas its activity was slightly bactericidal against Staphylococcus aureus at 37 degreesC. Higher bactericidal activity was detected against Escherichia coli O157:H7, Salmonella choleraesuis subsp. choleraesuis, Yersinia enterocolitica, Aeromonas hydrophila subsp. hydrophila and Campylobacter jejuni. A significant synergistic effect on L. monocytogenes and a slight additive effect on S. aureus after 24 h at 37degreesC were observed when reuterin was combined with nisin (100 IU/ml). The combination of reuterin with nisin did not enhance the antimicrobial effect of reuterin against Gram-negative pathogens. (C) 2004 Elsevier B.V. All rights reserved.