ASSESSMENT OF THYROID FUNCTION BY THE COMBINED USE OF THE SERUM PROTEIN-BOUND IODINE AND RESIN UPTAKE OF 131-I-TRIIODOTHYRONINE.
ASSESSMENT OF THYROID FUNCTION BY THE COMBINED USE OF THE SERUM PROTEIN-BOUND IODINE AND RESIN UPTAKE OF 131-I-TRIIODOTHYRONINE.
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通过结合使用血清蛋白结合碘和树脂摄取 131-I-三碘甲腺原氨酸来评估甲状腺功能。
DOI：
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发表时间：
1965
影响因子：
5.8
通讯作者：
D. B. Horn
中科院分区：
文献类型：
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作者：
F. Clark;D. B. Horn
比较了PBI的诊断准确性、~(131)I-T_3的树脂摄取量和它们的数学乘积(PBI×树脂摄取量)、“游离甲状腺素”指数，这是一个假定与血液中游离甲状腺素浓度成正比的任意数字。共对154例患者(108例临床甲状腺功能正常，其中23例妊娠，4例肾病综合征；30例甲状腺功能亢进，16例甲状腺功能低下)进行了三项指标的测定。17.4%的孕妇PBI值超出正常范围，93.3%的甲亢患者和100%的甲减患者PBI值超出正常范围。91.3%的孕妇、96.7%的甲状腺功能亢进症患者和87.5%的甲状腺功能减退患者的树脂摄取值超出正常范围。所有甲状腺机能亢进症和甲状腺功能减退患者的“游离甲状腺激素”指数都在正常范围之外，而所有孕妇的值都在正常范围内。虽然PBI和树脂摄取试验在甲状腺疾病的诊断中是非常令人满意的。
A comparison has been made between the diagnostic accuracy of the PBI, the resin uptake of 131I-T3 and their mathematical product (PBI × resin uptake), the “free thyroxine” index, an arbitrary figure, assumed to be proportional to the concentration of free thyroxine in the blood. The 3 parameters have been determined in a total of 154 patients (108 clinically euthyroid, of whom 23 were pregnant and 4 had the nephrotic syndrome; 30 thyrotoxic and 16 hypothyroid). PBI values outside the normal range were found in 17.4 %of the pregnant women and in 93.3 % of thyrotoxic and 100 % of hypothyroid patients. Resin uptake values outside the normal range were found in 91.3 % of the pregnant women, and in 96.7 % of thyrotoxic and 87.5 % of hypothyroid patients. All thyrotoxic and hypothyroid patients fell outside the normal range for the “free thyroxine” index, whereas all the pregnant women gave values inside the normal range. Although the PBI and resin uptake test are highly satisfactory in the diagnosis of thyroi...