Structure and function of declarative and nondeclarative memory systems
Structure and function of declarative and nondeclarative memory systems
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DOI：
10.1073/pnas.93.24.13515
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发表时间：
1996-11-26
影响因子：
11.1
通讯作者：
Zola, SM
中科院分区：
文献类型：
--
作者：
Squire, LR;Zola, SM
本文综述了人类和非人灵长类动物记忆系统的最新研究进展。最近的工作得出的三个主要结论是：(I)现在可以在评估分类学习、知觉运动技能学习、人工语法学习和原型抽象的广泛任务中研究非陈述性(无意识)学习的能力；(Ii)邻近海马结构的皮质区域，包括内嗅觉、周围和海马旁皮质，是支持陈述性(意识)记忆的内侧颞叶记忆系统的重要组成部分；(Iii)在人类中，仅限于海马结构的双侧损伤仍足以产生长达25年的严重顺行性健忘症和暂时性渐进性失忆症。
This article reviews recent studies of memory systems in humans and nonhuman primates. Three major conclusions from recent work are that (i) the capacity for nondeclarative (nonconscious) learning can now be studied in a broad array of tasks that assess classification learning, perceptuomotor skill learning, artificial grammar learning, and prototype abstraction; (ii) cortical areas adjacent to the hippocampal formation, including entorhinal, perirhinal, and parahippocampal cortices, are an essential part of the medial temporal lobe memory system that supports declarative (conscious) memory; and (iii) in humans, bilateral damage limited to the hippocampal formation is nevertheless sufficient to produce severe anterograde amnesia and temporally graded retrograde amnesia covering as much as 25 years.