Laughter is the Best Medicine? A Cross-Sectional Study of Cardiovascular Disease Among Older Japanese Adults.
Laughter is the Best Medicine? A Cross-Sectional Study of Cardiovascular Disease Among Older Japanese Adults.
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DOI：
10.2188/jea.je20150196
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发表时间：
2016-10-05
影响因子：
4.7
通讯作者：
Kondo N
中科院分区：
文献类型：
--
作者：
Hayashi K;Kawachi I;Ohira T;Kondo K;Shirai K;Kondo N
我们试图评估日常笑的频率与心脏病和中风之间的联系，在社区居住的日本老年妇女和男子。我们分析了2013年参加日本老年学评估研究的20934名65岁以上的人（10206名男性和10728名女性）的横断面数据。在邮件调查中，参与者提供了有关每日笑的频率，以及体重指数，人口统计学和生活方式因素，以及心血管疾病，高脂血症，高血压和抑郁症的诊断信息。即使调整了高脂血症、高血压、抑郁症、体重指数和其他危险因素，那些从不或几乎从不笑的人患心脏病的患病率也是那些每天都笑的人的1.21倍（95%CI，-1.03-1.41）。卒中的校正患病率为1.60（95% CI，1.24 - 2.06）。每天笑的频率与心血管疾病的发病率较低有关。这种关联不能用混杂因素（如抑郁症状）来解释。
We sought to evaluate the associations between frequency of daily laughter with heart disease and stroke among community-dwelling older Japanese women and men. We analyzed cross-sectional data in 20 934 individuals (10 206 men and 10 728 women) aged 65 years or older, who participated in the Japan Gerontological Evaluation Study in 2013. In the mail-in survey, participants provided information on daily frequency of laughter, as well as body mass index, demographic and lifestyle factors, and diagnoses of cardiovascular disease, hyperlipidemia, hypertension, and depression. Even after adjustment for hyperlipidemia, hypertension, depression, body mass index, and other risk factors, the prevalence of heart diseases among those who never or almost never laughed was 1.21 (95% CI, −1.03–1.41) times higher than those who reported laughing every day. The adjusted prevalence ratio for stroke was 1.60 (95% CI, 1.24–2.06). Daily frequency of laughter is associated with lower prevalence of cardiovascular diseases. The association could not be explained by confounding factors, such as depressive symptoms.