A SURVEY OF THE RESPONSES OF BIVALVE HEARTS TO THE MOLLUSCAN NEUROPEPTIDE FMRFAMIDE AND TO 5-HYDROXYTRYPTAMINE
A SURVEY OF THE RESPONSES OF BIVALVE HEARTS TO THE MOLLUSCAN NEUROPEPTIDE FMRFAMIDE AND TO 5-HYDROXYTRYPTAMINE
复制标题
双壳类心脏对软体动物神经肽 FMRF酰胺和 5-羟色胺反应的调查
DOI：
10.2307/1540986
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
M. Greenberg
中科院分区：
文献类型：
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作者：
S. D. Painter;M. Greenberg
观察了50种双壳软体动物的脑室对软体动物神经肽FMRFamide(Phe-Met-Arg-Phe NH2)和5-羟色胺(5HT)的机械反应。两者都主要是心脏兴奋，但都不是完全如此。FMRFamide对Cx的抑制或弱Cx抑制作用比5HT更常见，这种作用在古异齿亚类和异牙亚类中最为常见。相反，5-羟色胺只有很少的抑制作用，甚至是微弱的兴奋作用，这种作用在翼状突触亚类中最为常见。在一些双壳类动物中，对FMRFamide或5HT的反应惊人地一致，但在另一些双壳类动物中，它们的反应特征却截然不同。因此，FMRFamide既不是一种普通的心脏兴奋药，也不是一种普通的血清学制剂。
Ventricles from 50 species of bivalved molluscs were surveyed for their me chanical responses to the molluscan neuropeptide FMRFamide (Phe-Met-Arg-Phe NH2) and to 5-hydroxytryptamine (5HT). Both were predominantly cardioexci tatory, but neither was exclusively so. FMRFamide was inhibitory or weakly cx citatory more often than 5HT, and such effects were most common in the subclasses Paleoheterodonta and Heterodonta. In contrast, 5HT was only rarely inhibitory or even weakly excitatory, and such effects were most common in the subclass Pteriomorphia. The responses to FMRFamide or 5HT were strikingly uniform in some bivalve families, but characteristically diverse in others. Thus, FMRFamide is neither a general cardioexcitor nor a general serotonomimetic agent.