Arizonins, a new complex of antibiotics related to kalafungin. I. Taxonomy of the producing culture, fermentation and biological activity.
Arizonins, a new complex of antibiotics related to kalafungin. I. Taxonomy of the producing culture, fermentation and biological activity.
复制标题
Arizonins，一种与卡拉芬净相关的新型抗生素复合物。
DOI：
10.7164/antibiotics.41.1205
复制
发表时间：
1988
期刊：
影响因子：
--
通讯作者：
D. Hensey
中科院分区：
文献类型：
--
作者：
J. Karwowski;M. Jackson;R. J. Theriault;J. F. Prokop;M. Maus;C. Hansen;D. Hensey
arizonins 是一种与卡拉芬净相关的新型抗生素复合物，是在游动动线菌的发酵液中发现的。 AB660D-122。比较分类学研究表明，该培养物是一个新物种，因此被命名为 Actinoplanes arizonaensis sp。十一月该复合物的两个成员，arizonins A1 和 B1，对革兰氏阳性菌的致病菌株表现出中等至强效的体外抗菌活性。
The arizonins, a novel complex of antibiotics related to kalafungin, were discovered in the fermentation broth of Actinoplanes sp. AB660D-122. Comparative taxonomic studies indicated that the culture is a new species and therefore has been designated Actinoplanes arizonaensis sp. nov. Two members of the complex, arizonins A1 and B1, exhibit moderate to potent in vitro antimicrobial activity against pathogenic strains of Gram-positive bacteria.