Role of the Nasal Airway in Regulation of Airway Resistance During Hypercapnia and Exercise Second-Place Resident Award at 1982 Research Forum
Role of the Nasal Airway in Regulation of Airway Resistance During Hypercapnia and Exercise Second-Place Resident Award at 1982 Research Forum
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鼻气道在高碳酸血症和运动期间气道阻力调节中的作用 1982 年研究论坛住院医师二等奖
DOI：
10.1177/019459988409200311
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发表时间：
1984
影响因子：
3.4
通讯作者：
E. Kern
中科院分区：
文献类型：
--
作者：
J. Mertz;T. Mccaffrey;E. Kern
本文采用后面罩测压法测定了10名健康成年志愿者在运动和高碳酸血症时的鼻阻力。运动是通过在三个负载下兜售固定自行车来产生的。高碳酸血症是通过呼吸含有5%、6%和8% CO2的O2混合物产生的。结果表明：（1）鼻阻力随呼出CO2水平和运动水平的增加而线性降低，（2）每分钟通气量随呼出CO2水平和运动水平的增加而线性增加，（3）在高碳酸血症和运动期间，鼻阻力与每分钟通气量呈反比。在高碳酸血症和运动期间鼻阻力和每分钟通气量之间的恒定关系表明，鼻阻力由呼吸中枢调节以匹配呼吸需求水平。
Posterior mask rhinomanometry was used to measure nasal resistance during exercise and hypercapnia in 10 healthy adult volunteers. Exercise was produced by peddling a stationary bicycle at three loads. Hypercapnia was produced by breathing O2 mixtures containing 5%, 6%, and 8% CO2. The results showed that (1) nasal resistance decreases linearly as expired CO2 levels and exercise levels increase, (2) minute ventilation increases linearly as expired CO2 levels and exercise levels increase, and (3) nasal resistance varies inversely with minute ventilation during both hypercapnia and exercise. The constant relationship between nasal resistance and minute ventilation during hypercapnia and exercise suggests that nasal resistance is regulated by the respiratory center to match the level of respiratory demand.