Evaluating the uses of the total score and the domain scores in the Cognitive Abilities Screening Instrument, Chinese Version (CASI C-2.0): results of confirmatory factor analysis
Evaluating the uses of the total score and the domain scores in the Cognitive Abilities Screening Instrument, Chinese Version (CASI C-2.0): results of confirmatory factor analysis
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认知能力筛查仪中文版（CASI C-2.0）总分和领域分的使用评价：验证性因素分析结果
DOI：
10.1017/s1041610207005327
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发表时间：
2007
影响因子：
7
通讯作者：
Hsiu
中科院分区：
文献类型：
--
作者：
R. Tsai;Ker‐Neng Lin;Hsiao;Hsiu
摘要背景：认知能力筛查工具（CASI）由旨在测量认知能力九个领域的项目组成。其总分在临床上用于代表患者整体的基础认知能力。本研究旨在评估使用全领域总分作为整体认知衡量标准以及使用领域分数作为指定个人认知能力衡量标准的合理性。方法：为了证明使用所有项目的总分作为认知能力的总体衡量标准的合理性，进行了二阶验证性因素分析，以检查 CASI 中的项目是否对共同的基础结构有显着贡献。还通过检查指定域上项目的负载来检查域分数的使用。对 608 名患者（其中 68 名正常患者和 540 名阿尔茨海默病患者）的 CASI 数据进行了分析。结果二阶因子模型的拟合优度指标如下：WLSMV的CFI为0.912，WLSM的CFI为0.977； TLI 和 RMSEA 值分别为 0.975 和 0.090。公共底层构造上的项目负载都很显着（>0.3）。除长期记忆项目外，所有项目在各自子域上的负载也很显着。结论：CASI C-2.0 的项目不仅有助于分析相关认知领域得分，而且有助于形成患者潜在认知能力的整体衡量标准。
ABSTRACT Background: The Cognitive Abilities Screening Instrument (CASI) consists of items which are designed to measure the nine domains of cognitive ability. Its total score is used clinically to represent the overall underlying cognitive ability of the patient. This study aimed to evaluate the justification of the uses of the all-domain-total-score as an overall cognitive measure and the domain scores as measures of designated individual cognitive ability. Methods: To justify the use of total score of all the items as an overall measure of cognitive ability, a second-order confirmatory factor analysis was performed to examine whether the items in CASI contributed significantly to a common underlying construct. The uses of domain scores were also examined by inspecting the loadings of the items on their designated domains. The CASI data from 608 patients, 68 normal and 540 with Alzheimer's disease, were analyzed. Results The goodness-of-fit indices for the second-order factor model were as follows: CFI was 0.912 for WLSMV and 0.977 for WLSM; TLI and RMSEA values were 0.975 and 0.090 respectively. The loadings of the items on the common underlying construct are all salient (>0.3). The loadings of all but the long-term memory items on their respective subdomains were also salient. Conclusions: The items of the CASI C-2.0 were useful not only in profiling the correlated cognitive domain scores, but also in forming an overall measure of the underlying cognitive ability of the patients.