A FUNCTIONAL ANALYSIS OF SENSORY UNITS INNERVATING EPIGLOTTIS AND LARYNX
A FUNCTIONAL ANALYSIS OF SENSORY UNITS INNERVATING EPIGLOTTIS AND LARYNX
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DOI：
10.1016/0014-4886(68)90080-0
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发表时间：
1968-01-01
影响因子：
5.3
通讯作者：
STOREY, AT
中科院分区：
文献类型：
--
作者：
STOREY, AT
吞咽和咳嗽都是呼吸道的保护性反射，都可以从喉部开始。本研究的目的是找出被足够刺激所兴奋的喉感受器，并确定它们对刺激的放电特征。这是为每个保护性反射定义输入的重要参数的第一步。喉部触觉感受器似乎启动了这两种反射。这些受体是最肤浅的，很可能是自由的结局。75%的触觉感受器对水刺激也有反应，水刺激是吞咽的足够刺激。机械刺激促进了触觉单元的水反应。水刺激的换能器部位对全身麻醉药敏感，而机械换能器部位不敏感。机械刺激的放电模式、适应特征和持续时间取决于机械刺激的强度。频率和对水刺激的适应特性取决于溶液中的水浓度，而不是机械、渗透或微量钙的影响。放电频率和兴奋单位的模式被假设为启动适当反射的感觉放电的最重要参数。
Both swallowing and coughing, protective reflexes of the airway, can be initiated from the larynx. The purpose of this study was to find the laryngeal receptors excited by the adequate stimuli for these reflexes and to define the characteristics of their discharge to the stimuli. This represents the first step in defining the significant parameters of the input for each protective reflex. The laryngeal tactile receptors appear to initiate both reflexes. These receptors are the most superficial and are probably free endings. Seventy-five per cent of the tactile receptors are also responsive to water stimulation, the adequate stimulus for swallowing. The water response of tactile units is facilitated by mechanical stimulation. The transducer sites for water stimulation are sensitive to general anesthetics while the mechanotransducer sites are not. The discharge patterns, adaptation characteristics, and duration of discharge with mechanical stimulation are dependent on the strength of mechanical stimulation. The frequency and adaptation characteristics with water stimulation are dependent on the concentration of water in the solution and not on mechanical, osmotic, or trace-calcium effects. Frequency of discharge and the pattern of units excited are hypothesized as the most significant parameters of the sensory discharge initiating the appropriate reflex.