Autobiographical memory and post-psychotic depression in first episode psychosis
Autobiographical memory and post-psychotic depression in first episode psychosis
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DOI：
10.1348/014466504772812995
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发表时间：
2004-03-01
影响因子：
3.1
通讯作者：
Morris, E
中科院分区：
文献类型：
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作者：
Iqbal, Z;Birchwood, M;Morris, E
目标.在单相抑郁症中，早期生活事件的作用已被证明与获取此类自传体事件细节的缺陷（“过度概括记忆”）有关。在这项研究中，我们测试是否可以观察到类似的缺陷在精神病后抑郁症（PPD）的首发精神病。对一组29名患者在首次发病后的12个月内进行了随访，并监测PPD。结果。在样本组中，45%的人患上了PPD，这与过度概括记忆（p <0.05;效应量= 1.05）和对诊断的高度认识有关。我们的研究结果提出了一种可能性，即心理社会发展的异常可能导致精神病患者易患抑郁症。
Objectives. In unipolar depression, the action of early life events has been shown to be linked to a deficit in accessing details of such autobiographical events ('overgeneral memory'). In this study, we test whether a similar deficit can be observed in post-psychotic depression (PPD) in first-episode psychosis.Method. A group of 29 patients were followed up during the 12 months after their first onset, and monitored for PPD.Results. Of the sample group, 45% developed PPD, which was associated with overgeneral memory (p < .05; effect size = 1.05) and a heightened awareness of the diagnosis.Conclusions. Our findings raise the possibility that anomalies of psychosocial development may confer vulnerability to depression in psychosis.