Multivariate genetic analysis of cognitive abilities in an adolescent twin sample
Multivariate genetic analysis of cognitive abilities in an adolescent twin sample
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DOI：
10.1080/00049530410001734874
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发表时间：
2004-09-01
影响因子：
2.7
通讯作者：
Martin, NG
中科院分区：
文献类型：
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作者：
Luciano, M;Wright, MJ;Martin, NG
在包括245对同卵双胞胎(MZ)和298对异卵双胞胎(DZ)的经典双胞胎设计中，考察了检查时间、选择反应时间、延迟反应速度和准确度以及智商等认知指标之间的协变来源。结果表明，包含加性遗传效应和独特环境效应的因子模型最简约。在这个模型中，出现了一个一般的遗传认知因素，因素负荷在0.28到0.64之间。另外三个遗传因素解释了不同速度和延迟反应措施与智商之间剩余的遗传协变。然而，语言智商(54%)和操作智商(25%)的很大一部分遗传变异与这些较低级别的认知测量无关。独立的遗传智商变化可能反映了基本认知任务、检查时间和选择反应时间以及我们的工作记忆任务、延迟反应任务没有捕捉到的信息加工。独特的环境效应大多是不重叠的，部分代表了测试测量误差。
The sources of covariation among cognitive measures of Inspection Time, Choice Reaction Time, Delayed Response Speed and Accuracy, and IQ were examined in a classical twin design that included 245 monozygotic (MZ) and 298 dizygotic (DZ) twin pairs. Results indicated that a factor model comprising additive genetic and unique environmental effects was the most parsimonious. In this model, a general genetic cognitive factor emerged with factor loadings ranging from 0.28 to 0.64. Three other genetic factors explained the remaining genetic covariation between various speed and Delayed Response measures with IQ. However, a large proportion of the genetic variation in verbal (54%) and performance (25%) IQ was unrelated to these lower order cognitive measures. The independent genetic IQ variation may reflect information processes not captured by the elementary cognitive tasks, Inspection Time and Choice Reaction Time, nor our working memory task, Delayed Response. Unique environmental effects were mostly nonoverlapping, and partly represented test measurement error.