Control of meristem determinacy by trehalose 6-phosphate phosphatases is uncoupled from enzymatic activity
Control of meristem determinacy by trehalose 6-phosphate phosphatases is uncoupled from enzymatic activity
复制标题
DOI：
10.1038/s41477-019-0394-z
复制
发表时间：
2019-04-01
期刊：
影响因子：
18
通讯作者：
Jackson, David
中科院分区：
文献类型：
--
作者：
Claeys, Hannes;Vi, Son Lang;Jackson, David
分生组织命运受海藻糖 6-磷酸磷酸酶 (TPP) 调节，但其作用机制仍然神秘。玉米 TPP RAMOSA3 和 TPP4 的缺失会导致分生组织决定性降低和花序分枝增多。然而，对等位基因系列的分析表明酶活性和分支之间没有相关性，并且催化失活版本的 RA3 补充了 ra3 突变体。连同它们的核定位，这些发现表明 TPP 具有兼职功能。
Meristem fate is regulated by trehalose 6-phosphate phosphatases (TPPs), but their mechanism of action remains mysterious. Loss of the maize TPPs RAMOSA3 and TPP4 leads to reduced meristem determinacy and more inflorescence branching. However, analysis of an allelic series revealed no correlation between enzymatic activity and branching, and a catalytically inactive version of RA3 complements the ra3 mutant. Together with their nuclear localization, these findings suggest a moonlighting function for TPPs.