Establishment of Age- and Sex-Specific Reference Cerebral Ventricle Volumes.
Establishment of Age- and Sex-Specific Reference Cerebral Ventricle Volumes.
复制标题
建立特定年龄和性别的参考脑室体积。
DOI：
10.1016/j.wneu.2023.04.055
复制
发表时间：
2023
影响因子：
2
通讯作者：
Vargas,Jan
中科院分区：
文献类型：
--
作者：
Kellogg,RyanT;Park,MinS;Snyder,MHarrison;Marino,Alexandria;Patel,Sohil;Feng,Xue;Vargas,Jan
背景脑积水的诊断主要依赖于临床症状和影像学表现，包括脑室扩大。我们的目标是生成一个数据集的脑室容积利用非病理性计算机断层扫描（CT）扫描成人，以帮助定义参考ventricular size.MethodsWe进行了一项回顾性分析，非对比度头部CT成人在一个单一的机构，以确定患者谁经历了成像，并没有一个诊断为脑积水，脑室腹腔分流的历史，或治疗脑积水。一个卷积神经网络进行了训练，从各种年龄范围的手分割扫描，然后利用自动分割的整个dataset. Resultsacriles上866 CT扫描进行分割，以产生一个参考范围的体积为男性和女性的个人，年龄范围从18-99岁。所产生的数据被binned的年龄范围。ConclusionsWe已经开发出一种卷积神经网络，可以分割的成年患者的CT扫描在一定范围内的年龄的脑室。该网络用于测量非病理性头部CT的脑室容积，以产生几个年龄段的参考范围。该数据集可用于通过比较潜在病理扫描与参考脑室容积来辅助诊断脑积水。
BackgroundThe diagnosis of hydrocephalus is dependent on clinical symptoms and radiographic findings including ventriculomegaly. Our goal was to generate a data set of ventricular volume utilizing non-pathologic computed tomography (CT) scans for adults to help define reference ventricle size.MethodsWe performed a retrospective analysis of non-contrast head CTs for adults at a single institution to identify patients who had undergone imaging and did not have a diagnosis of hydrocephalus, history of ventriculoperitoneal shunting, or treatments for hydrocephalus. A convolutional neural network was trained on hand-segmented scans from a variety of age ranges and then utilized to automate the segmentation of the entire data set.ResultsVentricles on 866 CT scans were segmented to generate a reference range of volumes for both male and female individuals ranging in age from 18–99 years. The generated data were binned by age ranges.ConclusionsWe have developed a convolutional neural network that can segment the ventricles on CT scans of adult patients over a range of ages. This network was used to measure the ventricular volume of non-pathologic head CTs to produce reference ranges for several age bins. This data set could be utilized to aid in the diagnosis of hydrocephalus by comparing potentially pathologic scans to reference ventricular volumes.