Positon emission tomography: basic science and clinical practice
Positon emission tomography: basic science and clinical practice
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正发射断层扫描：基础科学与临床实践
DOI：
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发表时间：
2008
期刊：
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通讯作者：
M. Maisey
中科院分区：
文献类型：
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作者：
P. Valk;D. Bayley;D. Townsend;M. Maisey
这一全面的文本探讨了正电子发射断层扫描（PET）的各个方面。它将作为PET奖学金或核医学居民的优秀教科书。本文也将作为一个明确的参考PET研究人员和从业人员。PET成像领域需要来自不同学科的专家的合作。这些专家包括物理学家、放射化学家、数学家、技术专家、核医学医生和放射学家。这本书成功地争取了这些专家在PET领域的合作。这本书分为10个部分，涵盖了基础科学和当前和未来的临床科学应用，其中大部分文字致力于后者。每一章都是在各自领域受到国际尊重的专家撰写的。文本的整体组织允许书以连续或章节选择的方式阅读。各个章节既全面又简洁，为进一步阅读提供了足够的参考资料。书中有许多数字和图像，很好地融入了文本，并说明了所描述的概念。在适当的情况下，提供彩色图像和数字。关于PET仪器的历史、示踪剂发展和动力学建模的一章帮助读者理解临床PET应用的潜力和目前的局限性。基础科学部分包括仪器，放射化学，剂量学，重建，注册和动力学建模。在临床应用部分讨论的主题包括中枢神经系统，心肺系统，肿瘤学，传染病，儿科，药物开发和基因治疗的监测。还包括章节详细说明了技术专家的观点和技术设计和评估。这本书的一个独特之处在于它关注PET的未来。氟18氟脱氧葡萄糖是目前使用最广泛的PET示踪剂，但随着新的PET示踪剂的开发，提供缺氧，增殖，神经受体结合和基因治疗的功能成像，PET成像的全部潜力才刚刚出现。目前和未来的临床应用，这样的PET剂进行了讨论。这多学科，全面的文本将作为一个重要的参考，在迅速发展的PET领域。虽然其他书籍的PET是可用的，没有一个有广度和深度的信息所包含的这一可读性，权威性的文本。
This comprehensive text explores all facets of positron emission tomography (PET). It will serve as an excellent textbook for PET fellowships or for nuclear medicine residents. This text will also serve as a definitive reference for PET researchers and practitioners. The field of PET imaging requires the collaboration of experts from various disciplines. Such experts include physicists, radiochemists, mathematicians, technologists, and nuclear medicine physicians and radiologists. This book successfully enlists the collaboration of these experts in the PET field. The book is divided into 10 parts, which cover basic science and current and future clinical science applications, with the majority of the text dedicated to the latter. Experts who are internationally respected in their field wrote each chapter. The overall organization of the text allows the book to be read in a consecutive or a chapter-selective fashion. The individual chapters are both comprehensive and succinct, with adequate references for further reading. The book has many figures and images, which are well integrated into the text and illustrate the concepts described. When appropriate, color images and figures are provided. A chapter on the history of PET instrumentation, tracer development, and kinetic modeling helps the reader understand both the potential of and the current limitations on clinical PET applications. The basic science section covers instrumentation, radiochemistry, dosimetry, reconstruction, registration, and kinetic modeling. Topics that are discussed in the clinical applications section include the central nervous system, cardiorespiratory systems, oncology, infectious disease, pediatrics, drug development, and the monitoring of gene therapy. Also included are chapters detailing the technologist’s perspective and technology design and evaluation. A unique aspect of this book is that it focuses on the future of PET. Fluorine 18 fluorodeoxyglucose is currently the most widely used PET tracer, but with the development of new PET tracers that provide functional imaging of hypoxia, proliferation, neuroreceptor binding, and gene therapy, the full potential of PET imaging is just on the horizon. Current and future clinical applications of such PET agents are discussed in this text. This multidisciplinary, comprehensive text will serve as an essential reference in the rapidly developing PET field. While other books on PET are available, none has the breadth and depth of information contained in this readable, authoritative text.