Dimensional approaches to schizophrenia: A comparison of the Bern Psychopathology scale and the five-factor model of the Positive and Negative Syndrome Scale

Dimensional approaches to schizophrenia: A comparison of the Bern Psychopathology scale and the five-factor model of the Positive and Negative Syndrome Scale
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DOI:
10.1016/j.psychres.2016.03.032
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发表时间:
2016-05
影响因子:
11.3
通讯作者:
F. Lang;A. Müller-Stierlin;S. Walther;K. Stegmayer;T. Becker;M. Jäger
F. Lang;A. Müller-Stierlin;S. Walther;K. Stegmayer;T. Becker;M. Jäger
中科院分区:
医学2区
文献类型:
--
作者:
F. Lang;A. Müller-Stierlin;S. Walther;K. Stegmayer;T. Becker;M. Jäger

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其目的是检查BPS图的维度在多大程度上来自PANSS的五个因素,以探索这些可选维度方法在精神分裂症患者中的一致性水平。入选149例精神分裂症谱系障碍住院患者。采用伯尔尼精神病理学量表(BPS)和阳性与阴性症状量表(PANSS)评定精神病理症状。采用线性回归分析探讨各因素与BPS各条目之间的关系。对模式的稳健性进行了评估。对于积极和消极的症状和兴奋,这两种方法的重叠是可以理解的。PANSS阳性因子在抑制和去抑制方面与影响域的症状有关,PANSS负性因子以BPS的所有三个域的症状为抑制,PANSS兴奋因子以影响域的抑制和语言和运动域的去抑制相关联。结果表明,BPS的系统特有方法和五因素PANSS模型之间只有部分重叠。因此,对精神病理症状的纵向评估将是有意义的。
The aim was to examine to what extent the dimensions of the BPS map the five factors derived from the PANSS in order to explore the level of agreement of these alternative dimensional approaches in patients with schizophrenia. 149 inpatients with schizophrenia spectrum disorders were recruited. Psychopathological symptoms were assessed with the Bern Psychopathology Scale (BPS) and the Positive and Negative Syndrome Scale (PANSS). Linear regression analyses were conducted to explore the association between the factors and the items of the BPS. The robustness of patterns was evaluated. An understandable overlap of both approaches was found for positive and negative symptoms and excitement. The PANSS positive factor was associated with symptoms of the affect domain in terms of both inhibition and disinhibition, the PANSS negative factor with symptoms of all three domains of the BPS as an inhibition and the PANSS excitement factor with an inhibition of the affect domain and a disinhibition of the language and motor domains. The results show that here is only a partial overlap between the system-specific approach of the BPS and the five-factor PANSS model. A longitudinal assessment of psychopathological symptoms would therefore be of interest.