Comparison of the main sequence of reflexive saccades and the quick phases of optokinetic nystagmus
Comparison of the main sequence of reflexive saccades and the quick phases of optokinetic nystagmus
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DOI：
10.1136/bjo.85.12.1477
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发表时间：
2001-12-01
影响因子：
4.1
通讯作者：
Harris, CM
中科院分区：
文献类型：
--
作者：
Garbutt, S;Harwood, MR;Harris, CM
背景/目的：扫视主序列的异常是一个重要的发现，可能提示眼部运动、外周或中枢神经系统疾病的病理。在年轻或不合作的患者中，可能难以引起足够数量的扫视来测量主序列。通常认为视动性眼震（OKN）的快速时相与眼跳相同。如果是这样的话，使用OKN（一种容易诱发的无意识反应）作为引发多次扫视的简单方法是可行的。本研究的目的是确定是否反射性扫视和快速阶段的OKN确实是相同的，以及是否OKN快速阶段可以有一个临床的作用，在确定患者缓慢saccade. Methods OKN和反射性扫视记录从10名健康成人使用红外利姆布斯眼跟踪仪和双颞直流眼电图同时。通过以10-50度/秒围绕受试者旋转全视野图案化帘来刺激OKN。反射性扫视引起红色LED目标在5-20度eccentricity.Results-OKN快速阶段往往有较长的持续时间相比，扫视，但这些差异并不显着。OKN快速相的峰值速度略低于扫视，具有统计学显著性（p
Background/aims-Abnormalities in the saccadic main sequence are an important finding and may indicate pathology of the ocular motor periphery or central neurological disorders. In young or uncooperative patients it can be difficult eliciting a sufficient number of saccades to measure the main sequence. It is often assumed that the quick phases of optokinetic nystagmus (OKN) are identical to saccades. If this were the case, it would be feasible to use OKN, an involuntary response that is easily evoked, as a simple way of eliciting many saccades. The aim of this study was to determine whether reflexive saccades and the quick phases of OKN are indeed identical, and whether OKN quick phases could have a clinical role in identifying patients with slow saccades.Methods-OKN and reflexive saccades were recorded from 10 healthy adults using an infrared limbus eye tracker and bitemporal DC electro-oculography simultaneously. OKN was stimulated by rotating a full field patterned curtain around the subject at 10-50 degrees /s. Reflexive saccades were elicited to red LED targets at 5-20 degrees eccentricity.Results-OKN quick phases tended to have a longer duration compared to saccades, but these differences were not significant. OKN quick phases had a slightly lower peak velocity compared to saccades, which was statistically significant (p