Photomechanical basis of laser ablation of biological tissue.

Photomechanical basis of laser ablation of biological tissue.
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DOI:
10.1364/ol.19.001684
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发表时间:
1994-11
期刊:
影响因子:
3.6
通讯作者:
D. Albagli;M. Dark;L. Perelman;C. von Rosenberg;I. Itzkan;M. Feld
D. Albagli;M. Dark;L. Perelman;C. von Rosenberg;I. Itzkan;M. Feld
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
D. Albagli;M. Dark;L. Perelman;C. von Rosenberg;I. Itzkan;M. Feld

文献摘要

被引文献

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激光烧蚀生物组织的显微力学模型表明,当激光诱导的拉伸应力超过目标的极限拉伸强度时,烧蚀就开始了。我们表明,与文献中出现的激光诱导应力产生的一维热弹性模型不同,完整的三维解预测了目标表面显著拉伸应力的发展,精确地观察到烧蚀发生的地方。采用干涉测量技术测量了随时间变化的热弹性膨胀,亚阈值激光影响的结果与三维模型的预测结果完全一致。
The photomechanical model of laser ablation of biological tissue asserts that ablation is initiated when the laser-induced tensile stress exceeds the ultimate tensile strength of the target. We show that, unlike the one-dimensional thermoelastic model of laser-induced stress generation that has appeared in the literature, the full three-dimensional solution predicts the development of significant tensile stresses on the surface of the target, precisely where ablation is observed to occur. An interferometric technique has been developed to measure the time-dependent thermoelastic expansion, and the results for subthreshold laser fluences are in precise agreement with the predictions of the three-dimensional model.