Adolescents' motivations to abuse prescription medications

Adolescents' motivations to abuse prescription medications
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DOI:
10.1542/peds.2006-1644
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发表时间:
2006-12-01
期刊:
影响因子:
8
通讯作者:
Young, Amy
Young, Amy
中科院分区:
医学2区
文献类型:
--
作者:
Boyd, Carol J.;McCabe, Sean Esteban;Young, Amy

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目标.我们的目标是(1)确定青少年参与非医疗(非法)使用4类处方药的动机(原因)和(2)检查动机是否与药物滥用问题的高风险相关。2005年的样本(N = 1086)来自密歇根州东南部的一个种族多样化的学区,包括7日至12日年级的学生。通过使用自我管理的基于网络的调查收集数据,其中包括有关药物使用的问题和从事非医疗使用处方药的动机。在过去的一年中,12%的受访者参与了阿片类止痛药的非医疗使用:3%用于睡眠,2%作为镇静剂和/或焦虑,2%作为兴奋剂。从事处方药的非医疗用途的原因因药物分类而异。对于阿片类镇痛药,当动机的数量增加时,药物滥用筛查测试得分阳性的可能性也增加了。每增加一个被认可的动机,药物滥用筛查测试就会增加1.8倍。两组学生进行了比较(风险与自我治疗);与自我治疗组相比,那些支持阿片类药物非医疗使用多种动机的人(风险组)更有可能提高药物滥用筛选测试分数。那些处于危险组的人也更有可能使用大麻和酒精。这项探索性研究的结果值得进一步研究,因为处方药的非医疗用途的几个动机似乎与药物滥用问题的可能性更大。
OBJECTIVES. Our goals were to (1) determine adolescents' motivations (reasons) for engaging in the nonmedical (illicit) use of 4 classes of prescription medications and (2) examine whether motivations were associated with a higher risk for substance abuse problems.RESPONDENTS. The 2005 sample (N = 1086) was derived from one ethnically diverse school district in southeastern Michigan and included 7th-through 12th-grade students.METHODS. Data were collected by using a self-administered, Web-based survey that included questions about drug use and the motivations to engage in nonmedical use of prescription medication.RESULTS. Twelve percent of the respondents had engaged in nonmedical use of opioid pain medications in the past year: 3% for sleeping, 2% as a sedative and/or for anxiety, and 2% as stimulants. The reasons for engaging in the nonmedical use of prescription medications varied by drug classification. For opioid analgesics, when the number of motives increased, so too did the likelihood of a positive Drug Abuse Screening Test score. For every additional motive endorsed, the Drug Abuse Screening Test increased by a factor of 1.8. Two groups of students were compared (at-risk versus self-treatment); those who endorsed multiple motivations for nonmedical use of opioids (at-risk group) were significantly more likely to have elevated Drug Abuse Screening Test scores when compared with those who were in the self- treatment group. Those in the at-risk group also were significantly more likely to engage in marijuana and alcohol use.CONCLUSION. The findings from this exploratory study warrant additional research because several motivations for the nonmedical use of prescription medications seem associated with a greater likelihood of substance abuse problems.