Survival following extended operations for extracolonic invasion by colon cancer.
Survival following extended operations for extracolonic invasion by colon cancer.
复制标题
结肠癌结肠外侵犯的长期手术后的生存率。
DOI：
10.1001/archsurg.1982.01380290055010
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发表时间：
1982
影响因子：
--
通讯作者：
D. Elliott
中科院分区：
文献类型：
--
作者：
T. McGlone;W. Bernie;D. Elliott
在1972年至1976年治疗的460例结肠癌中，有24例是不寻常的。这些患者需要整块切除结肠和一个或多个相邻器官，以治疗结肠和这些器官之间的致密粘连。在66%的病例中，这些粘连代表了显微镜下的肿瘤浸润。淋巴结呈阳性的疾病，阶段C-3，只有四个标本。87%肿瘤的病理特征分化良好。手术死亡率为8%，2例患者分别于术后1年和3年死于复发。一名男子术后7年仍活着，疾病复发。19名患者（79%）在手术后存活5至9年，无疾病证据。与具有相似分期的Dukes' B和C疾病的患者相比，当进行扩展手术时，五年生存率显著提高。
Of 460 cases of colon cancer treated between 1972 and 1976, 24 were unusual. These patients required en bloc resection of the colon with one or more adjacent organs for dense adhesions between the colon and these organs. In 66% of the cases these adhesions represented microscopic tumor invasion. Lymph nodes were positive for disease, stage C-3, in only four specimens. The pathologic features of the tumor were well differentiated in 87%. The operative mortality was 8% and two patients died of recurrent disease one and three years postoperatively. One man is alive seven years postoperatively with recurrent disease. Nineteen patients (79%) are alive five to nine years following surgery with no evidence of disease. A comparison with patients with similarly staged Dukes' B and C disease shows a substantially improved survival at five years when extended operation is performed.