Bariatric Surgery Resistance: Using Preoperative Lifestyle Medicine and/or Pharmacology for Metabolic Responsiveness.
Bariatric Surgery Resistance: Using Preoperative Lifestyle Medicine and/or Pharmacology for Metabolic Responsiveness.
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DOI：
10.1007/s11695-017-2966-1
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发表时间：
2017-12
期刊：
影响因子：
2.9
通讯作者：
Malin SK
中科院分区：
文献类型：
--
作者：
Gilbertson NM;Paisley AS;Kranz S;Weltman A;Kirby JL;Hallowell PT;Malin SK
减肥手术是一种有效和持久的治疗肥胖及其相关的合并症的个人。然而，并非所有患者在减肥手术后都能达到减肥和/或心脏代谢目标，这表明有些人对减肥手术有抵抗力。这种抵抗的原因尚不清楚，但潜在的因素，如脂肪源性炎症，胰岛素抵抗，高血糖症和术前有氧健身与手术反应迟钝有关。运动、饮食和/或药理学在减少炎症和改善胰岛素作用以及身体功能方面是有效的。在此，我们提供的数据支持新的假设，即手术前干预可以提高对减肥手术有抵抗力的人的疾病解决。
Bariatric surgery is an effective and durable treatment for individuals with obesity and its associated comorbidities. However, not all patients meet weight loss and/or cardiometabolic goals following bariatric surgery, suggesting that some people are “bariatric surgery resistant”. The reason for this resistance is unclear, but potential factors, such as adiposity-derived inflammation, insulin resistance, hyperglycemia, and aerobic fitness prior to surgery have been related to blunted surgery responsiveness. Exercise, diet, and/or pharmacology are effective at reducing inflammation and improving insulin action as well as physical function. Herein, we present data that supports the novel hypothesis that intervening prior to surgery can enhance disease resolution in people who are resistant to bariatric surgery.
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影响因子：
3.2
作者：
Dodson, Rebecca M.;Firoozmand, Amin;Hyder, Omar;Tacher, Vania;Cosgrove, David P.;Bhagat, Nikhil;Herman, Joseph M.;Wolfgang, Christopher L.;Geschwind, Jean-Francois H.;Kamel, Ihab R.;Pawlik, Timothy M.
通讯作者：
Pawlik, Timothy M.
DOI：
10.1038/oby.2010.88
发表时间：
2010-12
期刊：
Obesity (Silver Spring, Md.)
影响因子：
--
作者：
Bond DS;Jakicic JM;Unick JL;Vithiananthan S;Pohl D;Roye GD;Ryder BA;Sax HC;Wing RR
通讯作者：
Wing RR
影响因子：
3.1
作者：
Alami, Ramzi S.;Morton, John M.;Curet, Myriam J.
通讯作者：
Curet, Myriam J.
影响因子：
2.9
作者：
Baldry, Emma L.;Leeder, Paul C.;Idris, Iskandar R.
通讯作者：
Idris, Iskandar R.
影响因子：
15.9
作者：
Coen, Paul M.;Tanner, Charles J.;Goodpaster, Bret H.
通讯作者：
Goodpaster, Bret H.