Correlation between visual acuity and interface reflectivity measured by pentacam following DSAEK
Correlation between visual acuity and interface reflectivity measured by pentacam following DSAEK
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DOI：
10.1111/aos.12217
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发表时间：
2014-02-01
影响因子：
3.4
通讯作者：
Reinhard, Thomas
中科院分区：
文献类型：
--
作者：
Heinzelmann, Sonja;Boehringer, Daniel;Reinhard, Thomas
目的：desceet剥离自动内皮角膜移植术（DSAEK）是一种先进的板层内皮角膜移植术。与穿透性角膜移植术相比，视力恢复似乎更快。然而，DSAEK的最终视觉效果似乎是有限的，特别是与Descemet膜内皮角膜移植术（DMEK）相比。没有移植失败的DSAEK病例通常没有显示出光学性能降低的任何明确的相关性。在这项研究中，我们试图将DSAEK后的视力与通过旋转Scheimpflug系统测量的界面反射率联系起来。方法：对13例DSAEK术后2-11个月使用pentacam的14只眼进行检查。在光轴中心的界面区域的反射率以及中央角膜厚度被确定。界面反射率与最佳眼镜矫正视力、角膜中央厚度及随访时间之间存在统计学相关性（多因子线性回归分析）。结果：界面反射率与BSCVA及随访时间有统计学意义。反射率在界面（金属）颗粒区域最高。界面反射率与角膜中央厚度的相关性无统计学意义。结论：我们提出了与DSAEK术后视力下降的可测量相关性，尽管移植物清晰。界面反射率与最佳眼镜矫正视力（BSCVA）呈负相关，表明界面区域的不规则或瘢痕形成可能影响DSAEK后的光学质量。
Purpose: Descemet-stripping automated endothelial keratoplasty (DSAEK) is an advanced method of lamellar endothelial keratoplasty. In comparison with penetrating keratoplasty, visual rehabilitation seems to be faster. Final visual outcome of DSAEK, however, seems to be limited, especially in comparison with Descemet membrane endothelial keratoplasty (DMEK). DSAEK cases without graft failure often do not show any definite correlate for the reduced optical performance. In this study, we tried to correlate visual acuity following DSAEK with interface reflectivity as measured by a rotating Scheimpflug system. Methods: We examined 14 eyes of 13 patients with the pentacam for 2-11months following DSAEK. Reflectivity of the interface region in the centre of the optical axis as well as central corneal thickness was determined. Statistical correlation between interface reflectivity and best spectacle-corrected visual acuity, central corneal thickness and follow-up time was drawn (multifactorial linear regression analysis). Results: Statistically significant correlation between interface reflectivity and BSCVA as well as follow-up time was found. Reflectivity was highest in regions of interface (metal) particles. There was no statistically significant correlation between interface reflectivity and central corneal thickness. Conclusion: We present a measurable correlate for reduced visual outcome following DSAEK despite a clear graft. Inverse correlation between interface reflectivity and best spectacle-corrected visual acuity (BSCVA) indicates that irregularities or scarring in the interface region may influence the optical quality following DSAEK.