The infarct location predicts progressive motor deficits in patients with acute lacunar infarction in the lenticulostriate artery territory
The infarct location predicts progressive motor deficits in patients with acute lacunar infarction in the lenticulostriate artery territory
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DOI：
10.1016/j.jns.2010.02.027
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发表时间：
2010-06-15
影响因子：
4.4
通讯作者：
Murai, Tomohiko
中科院分区：
文献类型：
--
作者：
Ohara, Tomoyuki;Yamamoto, Yasumasa;Murai, Tomohiko
背景和目的：急性腔隙性脑梗死患者常在入院后出现运动功能障碍。我们的研究的目的是确定PMD的预测因素，使用的结果，扩散加权成像（DWI）的admission.Methods：从2005年1月至2008年12月，我们研究了60例连续急性腔隙性脑梗死患者在LSA领土发病后24小时内。为了确定PMD的预测因素，对包括血管危险因素和DWI结果在内的临床特征进行了评价。DWI结果包括梗死灶的大小、位置及DWI上可见梗死灶的层数。就位置而言，后部型定义为位于包括放射冠在内的切片中从顶部起第二个切片上的放射冠后部的梗死。结果：26例患者（43%）表现出PMD。单因素分析显示年龄≥ 75岁（P=0.03）、女性（P=0.04）、梗死切片数≥ 3（P=0.04）、后壁型梗死（P
Background and purpose: Patients with acute lacunar infarction in the lenticulostriate artery (LSA) territory often show progression of motor deficits (PMD) after admission. The purpose of our study is to identify predictors for PMD using the findings of diffusion-weighted imaging (DWI) on admission.Methods: From January 2005 to December 2008, we studied 60 consecutive patients with acute lacunar infarction in the LSA territory within 24 h after onset. To identify predictors for PMD, clinical characteristics including vascular risk factors and DWI findings were evaluated. DWI findings included the size and location of the infarcts and the slice numbers of infarcts visible on DWI. For the location, posterior type was defined as an infarct located in the posterior part of corona radiata on the second slice from the top among slices including corona radiata.Results: Twenty-six patients (43%) showed PMD. In univariate analysis, age >= 75 (P=0.03), female sex (P=0.04), infarct slice number >= 3 (P=0.04), and posterior type infarct (P