Ability of magnetic resonance elastography to assess taut bands
Ability of magnetic resonance elastography to assess taut bands
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DOI：
10.1016/j.clinbiomech.2007.12.002
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发表时间：
2008-06-01
影响因子：
1.8
通讯作者：
An, Kai-Nan
中科院分区：
文献类型：
--
作者：
Chen, Qingshan;Basford, Jeffrey;An, Kai-Nan
背景肌筋膜张紧带是诊断肌筋膜疼痛的核心。尽管它们很重要，但我们仍然缺乏能够客观确认其性质或位置的实验室测试或成像技术。本研究探讨磁共振弹性成像的能力，定位和调查的基础上，他们对剪切波传播的影响肌筋膜拉紧带的机械性能。本研究分三个阶段进行。第一个涉及凝胶体模中拉紧带的成像，第二个是体模实验的有限元建模，第三个是涉及八个人类受试者的初步评估，其中四个人有，四个人没有肌筋膜疼痛。实验用1.5T磁共振成像扫描仪进行。剪切波传播成像和剪切刚度重建使用匹配滤波刚度反演算法。凝胶体模成像和有限元计算实验支持我们的假设，拉紧带可以成像的基础上，其出色的剪切刚度。初步的人体研究显示，相对于对照组或附近未受累肌肉，受累受试者的拉紧带区域的剪切刚度在统计学上显著增加50-100%（P = 0.01）。这项研究表明，磁共振弹性成像可能有一个潜在的客观特点肌筋膜拉紧带，到目前为止，只能通过临床医生的手指检测。(c)2007爱思唯尔有限公司保留所有权利。
Background Myofascial taut bands are central to diagnosis of myofascial pain. Despite their importance, we still lack either a laboratory test or imaging technique capable of objectively confirming either their nature or location. This study explores the ability of magnetic resonance elastography to localize and investigate the mechanical properties of myofascial taut bands on the basis of their effects on shear wave propagation.Methods. This study was conducted in three phases. The first involved the imaging of taut bands in gel phantoms, the second a finite element modeling of the phantom experiment, and the third a preliminary evaluation involving eight human subjects-four of whom had, and four of whom did not have myofascial pain. Experiments were performed with a 1.5 T magnetic resonance imaging scanner. Shear wave propagation was imaged and shear stiffness was reconstructed using matched filtering stiffness inversion algorithms.Findings. The gel phantom imaging and finite element calculation experiments supported our hypothesis that taut bands can be imaged based on its outstanding shear stiffness. The preliminary human study showed a statistically significant 50-100% (P = 0.01) increase of shear stiffness in the taut band regions of the involved subjects relative to that of the controls or in nearby uninvolved muscle.Interpretation. This study suggests that magnetic resonance elastography may have a potential for objectively characterizing myofascial taut bands that have been up to now detectable only by the clinician's fingers. (c) 2007 Elsevier Ltd. All rights reserved.