FDG PET imaging in the evaluation of post-transplant lymphoproliferative disorder following renal transplantation
FDG PET imaging in the evaluation of post-transplant lymphoproliferative disorder following renal transplantation
复制标题
FDG PET 成像评估肾移植后移植后淋巴细胞增殖性疾病
DOI：
10.1097/00006231-200512000-00010
复制
发表时间：
2005
影响因子：
1.5
通讯作者：
B. Franc
中科院分区：
文献类型：
--
作者：
Angus R O'Conner;B. Franc
目的评价氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)对肾移植术后淋巴组织增生性疾病(PTLD)的诊断价值。方法回顾5例经病理证实的同种异体肾移植后PTLD患者的FDG PET检查结果，并与常规影像检查结果进行比较。对3例PTLD患者在治疗过程中不同时间点的PET检查进行了回顾，并与临床结果进行了比较。结果正电子发射计算机断层成像确定了横断面成像所见的所有病变部位，明确了不确定意义的部位，并在五分之二的患者中发现了额外的病变。早期随访成像影响了三名患者中的两名患者的PTLD治疗。结论FDGPET在PTLD的分期和随访中是一种有效的影像手段。
ObjectivesTo assess the usefulness of fluorodeoxyglucose positron emission tomography (FDG PET) in the evaluation of post-transplant lymphoproliferative disorder (PTLD) following renal transplantation. MethodsStaging FDG PET examinations were reviewed in five patients with biopsy proven post-renal allograft PTLD and compared with conventional imaging. Follow-up PET examinations of three patients at various points during their therapy for PTLD were also reviewed and compared with clinical outcome. ResultsPET imaging identified all disease sites seen at cross-sectional imaging, clarified sites of uncertain significance and detected additional disease in two out of five patients. Early follow-up imaging impacted PTLD management in two of three patients. ConclusionIn this limited series FDG PET was an effective imaging modality in the staging and follow-up of PTLD.