The Quest toward limb regeneration: a regenerative engineering approach.
The Quest toward limb regeneration: a regenerative engineering approach.
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DOI：
10.1093/rb/rbw002
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发表时间：
2016-06
影响因子：
6.7
通讯作者：
Nair LS
中科院分区：
文献类型：
--
作者：
Laurencin CT;Nair LS
解决人类肢体丧失的临床重大挑战的圣杯是开发创新策略来再生截肢。在过去的几十年里，对再生、干细胞科学、材料科学与工程、物理学和新型手术方法的科学理解取得了显着进展，为面对这一巨大挑战和解决人类伤口愈合的局限性提供了再生工具箱。在这里，我们讨论的收敛方法提出的再生工程领域使用再生工具箱设计和开发新的翻译策略肢体再生。
The Holy Grail to address the clinical grand challenge of human limb loss is to develop innovative strategies to regrow the amputated limb. The remarkable advances in the scientific understanding of regeneration, stem cell science, material science and engineering, physics and novel surgical approaches in the past few decades have provided a regenerative tool box to face this grand challenge and address the limitations of human wound healing. Here we discuss the convergence approach put forward by the field of Regenerative Engineering to use the regenerative tool box to design and develop novel translational strategies to limb regeneration.