VISUAL-ACUITY IN HOODED RATS - EFFECTS OF SUPERIOR COLLICULAR OR POSTERIOR NEOCORTICAL LESIONS
VISUAL-ACUITY IN HOODED RATS - EFFECTS OF SUPERIOR COLLICULAR OR POSTERIOR NEOCORTICAL LESIONS
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DOI：
10.1016/0006-8993(78)90076-8
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发表时间：
1978-01-01
期刊：
影响因子：
2.9
通讯作者：
DEAN, P
中科院分区：
文献类型：
--
作者：
DEAN, P
采用回避技术，使用大的、高对比度的高平均亮度的方波光栅，测量了戴帽大鼠的视觉分辨力。在消融后皮质或上级丘之前和之后进行测量。皮质病变包括纹状体和颞叶皮质，并引起整个背外侧膝状体核的逆行变性。两组在术后首次测试时均未显示出检测到粗方波光栅的迹象。丘损伤的动物很快重新学习;他们的敏锐度没有改变。经过大量的训练后，4只皮质动物中有3只重新学会了检测光栅。他们的视力下降到约1/3的术前值。在大鼠的膝状皮质通路显然进行了足够的信息正常检测的高空间频率。从上级丘到新皮层的通路是否也通过丘脑中继传递了这一信息尚不确定。
The visual resolution acuity of hooded rats was measured with an avoidance technique, using large, high contrast square-wave gratings of high mean luminance. Measurements were taken before and after ablation of either posterior cortex or the superior colliculus. The cortical lesions included both striate and temporal cortex, and caused retrograde degeneration throughout the dorsal lateral geniculate nucleus. Neither group showed signs of detecting even coarse square-wave gratings when first tested after operation. The animals with collicular lesions quickly relearned; their acuity was unaltered. After extensive training 3 of 4 cortical animals relearned to detect gratings. Their acuity was reduced to about 1/3 its preoperative value. In rats the geniculocortical pathway apparently carried sufficient information for the normal detection of high spatial frequencies. Whether a pathway from superior colliculus to neocortex via a thalamic relay also carried this information was uncertain.