Measurement of visual sensitivity in migraine: Validation of two scales and correlation with visual cortex activation
Measurement of visual sensitivity in migraine: Validation of two scales and correlation with visual cortex activation
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DOI：
10.1177/0333102414547782
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发表时间：
2015-06-01
期刊：
影响因子：
4.9
通讯作者：
Detre, John
中科院分区：
文献类型：
--
作者：
Cucchiara, Brett;Datta, Ritobrato;Detre, John
目的本文的目的是比较发作间期和发作期的视觉敏感性偏头痛和对照组使用两个已发表的问卷，并与视觉皮层activation.Methods（MWA，n=51）和无（MwoA，n=45）先兆偏头痛和对照组（n=45）的生理措施相关的反应，并进行BOLD功能磁共振成像与视觉刺激。用视觉不适评分（VDS）评价发作间期，用偏头痛恐惧评分（MPS）评价发作期视觉敏感度。结果与对照组相比，MWA组和MwoA组的VDS均显著增高（均P
Objective The objectives of this article are to compare interictal and ictal visual sensitivity between migraine and controls using two published questionnaires, and to correlate responses with a physiologic measure of visual cortex activation.Methods Migraine with (MWA, n=51) and without (MwoA, n=45) aura and control individuals (n=45) were enrolled and underwent BOLD fMRI with a visual stimulus. The visual discomfort score (VDS) assessed interictal and the migraine photophobia score (MPS) assessed ictal visual sensitivity.Result VDS was significantly higher both in MWA and MwoA vs controls (both p