1 Hz repetitive transcranial magnetic stimulation of the unaffected hemisphere ameliorates contralesional visuospatial neglect in humans
1 Hz repetitive transcranial magnetic stimulation of the unaffected hemisphere ameliorates contralesional visuospatial neglect in humans
复制标题
DOI：
10.1016/s0304-3940(02)01283-1
复制
发表时间：
2003-01-16
影响因子：
2.5
通讯作者：
Fierro, B
中科院分区：
文献类型：
--
作者：
Brighina, F;Bisiach, E;Fierro, B
本研究的目的是探讨低频重复经颅磁刺激（rTMS）是否可以改善未受影响的半球的视觉空间忽视。我们治疗了三名右脑损伤的左忽视患者。在左后顶叶皮层上每隔一天给予900个脉冲（1 Hz频率），持续2周。患者进行了一个计算机化的任务，需要长度判断prebisected线，tachistoscopically提出了150毫秒。相对于rTMS的任务是15天前，在开始时，结束时和15天后。在这些时候，患者也进行线平分和时钟绘制任务。rTMS诱导视觉空间表现的显着改善，15天后保持不变。患者在时间3和时间4的表现也改善了关于线平分和时钟绘制任务。(C)2002爱思唯尔科学爱尔兰有限公司保留所有权利。
The aim of the study was to investigate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) over the unaffected hemisphere can ameliorate visuospatial neglect. We treated three right brain damaged patients with left neglect. 900 pulses (1 Hz frequency) were given over left posterior parietal cortex every other day for 2 weeks. Patients performed a computerized task requiring length judgement of prebisected lines, tachistoscopically presented for 150 ms. With respect to rTMS the task was given 15 days before, at the beginning, at the end and 15 days after. At these times patients performed also line bisection and clock drawing tasks. rTMS induced a significant improvement of visuo-spatial performance that remained quite unchanged 15 days after. Patients performance at Time 3 and 4 improved also as concerns line bisection and clock drawing tasks. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.