POSTIRRADIATION ATROPHIC CHANGES OF BONE AND RELATED COMPLICATIONS
POSTIRRADIATION ATROPHIC CHANGES OF BONE AND RELATED COMPLICATIONS
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DOI：
10.1148/117.3.677
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发表时间：
1975-01-01
期刊：
影响因子：
19.7
通讯作者：
JOHNSON, RG
中科院分区：
文献类型：
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作者：
HOWLAND, WJ;LOEFFLER, RK;JOHNSON, RG
对接受 200 kV 照射的 49 名患者、接受 25 MeV 电子感应加速器光子照射的 50 名患者以及接受钴 60 照射的 20 名患者进行了照射后肩带放射照相可见变化的序列分析。这些变化与剂量相关，在千伏电压组中最为明显，但也在兆伏电压治疗后发生。萎缩性改变可能并发骨折、真性坏死、真性骨炎或肉瘤。这些萎缩性变化具有与皮肤和粘膜发生的萎缩性变化相似的临床意义。应用于这些变化的术语放射性坏死和放射性骨炎应该被放弃，因为它们意味着比实际存在的过程更严重的过程。如果可能，应避免活检，因为创伤和继发感染可能导致真正的坏死。
The sequence of radiographically visible changes about the shoulder girdle following irradiation was analyzed in 49 patients who received 200 kV irradiation, in 50 who received 25 MeV betatron photon irradiation, and in 20 who received cobalt-60 irradiation. The changes were dose related and were most evident in the kilovoltage group, but also occurred following megavoltage therapy. Atrophic changes may be complicated by fracture, true necrosis, true osteitis or sarcoma. These atrophic changes have clinical significance similar to the atrophic changes that occur in skin and mucous membranes. The terms radionecrosis and radiation osteitis as applied to these changes should be abandoned since they imply a more serious process than is actually present. Biopsy should be avoided if possible since trauma and secondary infection could lead to true necrosis.