Septum formation in Aspergillus nidulans.
Septum formation in Aspergillus nidulans.
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DOI：
10.1139/b95-275
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发表时间：
1995-12
影响因子：
5.4
通讯作者：
M. Momany;Jennifer L. Morrell;Steven D. Harris;J. E. Hamer
中科院分区：
文献类型：
--
作者：
M. Momany;Jennifer L. Morrell;Steven D. Harris;J. E. Hamer
丝状真菌形成由隔膜分隔的多细胞菌丝。以.在有丝分裂完成后，需要组装隔带才能形成nidulans。最近的观察表明，这条带是一个动态结构，由肌动蛋白，septin和一个peptin组成。此外，装配是依赖于一个保守的蛋白激酶级联调节有丝分裂退出和分隔在酵母。菌丝分化可能反映了细胞周期蛋白依赖性激酶活性对这一级联反应的调节。本文就隔带组装的动力学和调控机制进行综述。
Filamentous fungi form multicellular hyphae that are partitioned by septa. In A. nidulans, septum formation requires the assembly of a septal band following the completion of mitosis. Recent observations show that this band is a dynamic structure composed of actin, a septin and a formin. In addition, assembly is dependent upon a conserved protein kinase cascade that regulates mitotic exit and septation in yeast. Hyphal differentiation may reflect the regulation of this cascade by cyclin-dependent kinase activity. In this review, the dynamics and regulation underlying the assembly of the septal band are discussed.