Interaction of bradykinin with angiotensin, prostacyclin, and nitric oxide in myocardial preservation.
Interaction of bradykinin with angiotensin, prostacyclin, and nitric oxide in myocardial preservation.
复制标题
缓激肽与血管紧张素、前列环素和一氧化氮在心肌保存中的相互作用。
DOI：
10.1111/j.1749-6632.1999.tb09244.x
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发表时间：
1999
影响因子：
5.2
通讯作者：
Engelman,RM
中科院分区：
文献类型：
--
作者：
Sato,M;Das,DK;Engelman,RM
翻译后摘要：这篇评论的重点是缓激肽在心肌缺血性心脏骤停的心肌保护的重要性。缓激肽是心脏在缺血应激时自发释放的一种信号，可被视为心脏抵抗缺血的一种生存信号。缓激肽似乎通过控制其他细胞内调节剂（如前列环素和一氧化氮）的释放而发挥信号分子的作用，这些调节剂也对缺血心肌产生有益作用。
Abstract:This review focuses on the importance of bradykinin in myocardial preservation during ischemic arrest. Bradykinin is released from the heart spontaneously in response to ischemic stress, which may be viewed as a survival signal of the heart against ischemia. Bradykinin appears to function as a signaling molecule by controlling the release of other intracellular modulators, such as prostacyclins and nitric oxide, which also exert beneficial effects on the ischemic myocardium.