Ultrasound-guided fine-needle aspiration biopsy in nonpalpable thyroid nodules: Is it useful in infracentimetric nodules?
Ultrasound-guided fine-needle aspiration biopsy in nonpalpable thyroid nodules: Is it useful in infracentimetric nodules?
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DOI：
10.3349/ymj.2003.44.4.635
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发表时间：
2003-08-30
影响因子：
2.4
通讯作者：
Yoo, HS
中科院分区：
文献类型：
--
作者：
Kim, SJ;Kim, EK;Yoo, HS
本研究的目的是评价超声引导下细针穿刺活检（US-FNAB）对不可触及的甲状腺病变（包括病灶下结节）的评价和治疗计划的有效性。121例患者接受了149个不可触及的实性结节的US-FNAB。65例患者接受了手术，84例患者随访至少36个月。US-FNAB的结果与病理结果和临床随访结果相关。结节直径0.3 ~ 2cm，平均0.8cm。在这149个结核中，115个为厘米以下，34个为厘米或厘米以上。在149个甲状腺结节中，US-FNAB真阳性43个，真阴性90个，假阳性7个，假阴性1个。在8例病例中，病变采样不充分。超声细针穿刺诊断肺结节的敏感性、特异性、阳性预测值、阴性预测值和准确性分别为96.9%、93.4%、86.1%、98.6%和94.4%;诊断肺结节的敏感性、特异性、阳性预测值和阴性预测值分别为100%、90.5%、85.7%、100%和93.9%。在厘米级和厘米级或厘米级以上结节之间的结果没有显著差异。总之，US-FNAB是一个有用的工具，用于确定不可触及的实性甲状腺结节的治疗计划，即使当直径小于1厘米，并显示出高灵敏度，特异性和准确性。
The purpose of this study was to evaluate the usefulness of an ultrasound-guided fine-needle aspiration biopsy (US-FNAB) for the evaluation and treatment planning of nonpalpable thyroid lesions, including infracentimetric nodules. One hundred and twenty one patients underwent US-FNAB for 149 non-palpable solid nodules. Sixty-five patients underwent surgery, and 84 were followed up for at least 36 months. The results of the US-FNAB correlated with the pathological findings and clinical follow-up results. The nodules ranged from 0.3 to 2 cm in diameter, with a mean of 0.8 cm. Among the 149 nodules, 115 were infracentimetric and 34 were centimetric or supracentimetric in size. Of the 149 thyroid nodules, US-FNAB was true positive in 43, true negative in 90, false positive in 7 and false negative in 1. In 8 cases, the lesion was inadequately sampled. The sensitivity, specificity positive predictive value, negative predictive value an accuracy of the US-FNAB for the infracentimetric nodules were 96.9, 93.4, 86.1, 98.6 and 94.4%, and for the centimetric or supracentimetric nodules, were 100, 90.5, 85.7, 100 and 93.9%, respectively. There were no significant differences in the results between the infracentimetric and centimetric or supracentimetric nodules. In conclusion, an US-FNAB is a useful tool for determining the treatment plan of non-palpable solid thyroid nodules, even when less than I cm in diameter, and shows high sensitivity, specificity and accuracy.