A Novel Animal Model for Simulating Scarring After Cleft Lip Repair.
A Novel Animal Model for Simulating Scarring After Cleft Lip Repair.
复制标题
模拟唇裂修复后疤痕的新型动物模型。
DOI：
10.1089/fpsam.2020.0525
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发表时间：
2022
影响因子：
2
通讯作者：
Scott,AndrewR
中科院分区：
文献类型：
--
作者：
Papathanasiou,Evangelos;Trotman,CarrollAnn;Beale,Corinna;VanDyke,ThomasE;Scott,AndrewR
材料和方法所有实验均由Tufts大学机构动物护理和使用委员会批准。使用12只6周龄雄性新西兰白色家兔，体重2-3 kg。对每只家兔的自然发生的正中唇裂进行手术加宽和修复，以模拟左侧单侧唇裂的闭合，类似于Bardach和艾斯巴赫描述的技术，但进行了不同的修改。第五、六条
Materials and MethodsAll experiments were approved by the Tufts University Institutional Animal Care and Use Committee. Twelve, 6-week-old male New Zealand white rabbits weighing 2–3 kg were utilized. The naturally occurring, median cleft lip of each rabbit was surgically widened and repaired to simulate closure of a left unilateral cleft lip, similar to a technique described by Bardach and Eisbach but with distinct modifications. 5, 6