Psychotherapy for cancer patients.
Psychotherapy for cancer patients.
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DOI：
10.1177/0091217416680197
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发表时间：
2016-07-01
影响因子：
2
通讯作者：
Zainal, Nor Zuraida
中科院分区：
文献类型：
--
作者：
Chong Guan, Ng;Mohamed, Salina;Zainal, Nor Zuraida
目的心理治疗是治疗癌症患者心理困扰的一种常用的非药物治疗方法。心理疗法的好处是有记录的，但提出的心理疗法的类型是多种多样的。鉴于上一次文献综述是在十年前，并且没有对这一主题进行定量分析，我们再次批判性地、系统地回顾了所有已发表的癌症患者心理治疗试验。方法检索PubMed和EMBASE，共检索到17篇关于癌症患者6种心理治疗的临床试验。结果纳入定量分析的有4个涉及辅助心理治疗的试验。每项试验都表明，心理治疗改善了癌症患者的生活质量和应对能力。在心理干预后，痛苦、焦虑和抑郁也有所减少。然而，每种类型的心理治疗的临床试验的数量和质量都很差。对涉及辅助心理治疗的四项试验的荟萃分析显示，抑郁症没有显著变化，焦虑症只有短期显著改善，但不到一年-标准化平均差异为-0.37（95%置信区间（CI）=-0.57，-0.16），4个月为-0.21（95% CI=-0.42，-0.01），12个月为0.03（95% CI=-0.19，0.24）。结论心理治疗对癌症患者的疗效尚不理想。有必要对这一主题进行更严格和精心设计的临床试验。
Objective Psychotherapy is a common non-pharmacological approach to help cancer patients in their psychological distress. The benefit of psychotherapies was documented, but the types of psychotherapies proposed are varied. Given that the previous literature review was a decade ago and no quantitative analysis was done on this topic, we again critically and systematically reviewed all published trials on psychotherapy in cancer patients. Method We identified 17 clinical trials on six types of psychotherapy for cancer patients by searching PubMed and EMBASE. Result There were four trials involved adjunct psychological therapy which were included in quantitative analysis. Each trial demonstrated that psychotherapy improved the quality of life and coping in cancer patients. There was also a reduction in distress, anxiety, and depression after a psychological intervention. However, the number and quality of clinical trials for each type of psychotherapy were poor. The meta-analysis of the four trials involved adjunct psychological therapy showed no significant change in depression, with only significant short-term improvement in anxiety but not up to a year-the standardized mean differences were -0.37 (95% confidence interval (CI)=-0.57, -0.16) at 2 months, -0.21 (95% CI=-0.42, -0.01) at 4 months, and 0.03 (95 % CI=-0.19, 0.24) at 12 months. Conclusion The evidence on the efficacy of psychotherapy in cancer patients is unsatisfactory. There is a need for more rigorous and well-designed clinical trials on this topic.