A Store-and-Forward Tele-Audiology Solution to Promote Efficient Screenings for Ototoxicity during Cisplatin Cancer Treatment
A Store-and-Forward Tele-Audiology Solution to Promote Efficient Screenings for Ototoxicity during Cisplatin Cancer Treatment
复制标题
DOI：
10.3766/jaaa.15028
复制
发表时间：
2015-10-01
影响因子：
1.2
通讯作者：
Jacobs, Peter
中科院分区：
文献类型：
--
作者：
Dille, Marilyn F.;McMillan, Garnett P.;Jacobs, Peter
背景：远程听力学改善了医疗保健的可及性，控制了成本，提高了效率。我们已经开发并验证了一种设备，耳毒性识别设备（OtoID），它可以在化疗治疗期间对患者进行远程听力监测。设计方面，如病人自我测试和文本的结果，以听力学诊所是这个设备的重要特点。目的：本文的目的是目前的OtoID听力筛选的功效和有效性。研究设计：本研究采用重复测量设计，研究样本：21名接受顺铂化疗的退伍军人被招募入本研究，数据收集和分析：参与者在每次顺铂治疗时使用OtoID进行测试，由听力学家使用手动测试模式，参与者使用自动测试模式。测试的灵敏度和特异性是从检测（是/否）的美国言语-语言-听力协会（阿莎）在hearing.Results的变化：OtoID有一个测试的灵敏度为80.6%，特异性为85.3%。对自动OtoID识别的阿莎偏移概率进行逻辑回归模型分析。分别拟合模型，以确定年龄、耳毒性敏感范围（SRO）内的平均基线阈值和顺铂剂量对阳性听力变化结果概率的影响。还包括相互作用，以评估这些影响的灵敏度和假阳性率的自动化测试。结果表明，年龄，基线听力的SRO频率，或顺铂dose.Conclusions：OtoID自动测试可以推荐使用的统计学显着影响。自动化测试提供了显著的人员效率。最近添加到设备中的具有简单文本消息功能的调制解调器提高了这些效率。
Background: Tele-audiology improves access, controls cost, and improves efficiency of many aspects within health care. We have developed and validated a device, the ototoxicity identification device (OtoID), which enables remote hearing monitoring by a patient during chemotherapy treatment. Aspects of the design such as patient self-testing and texting of results to the audiology clinic are important features of this device.Purpose: The purpose of this article is to present the efficacy and effectiveness of the OtoID hearing screener. Research Design: A repeated measures design was used in this study.Study Sample: Twenty-one veterans undergoing cisplatin chemotherapy were recruited in this study.Data Collection and Analysis: Participants were tested using the OtoID at each cisplatin treatment by an audiologist using the manual mode of test and the participant using the automated mode of test. Test sensitivity and specificity were developed from the detection (yes/no) of an American Speech-Language-Hearing Association (ASHA) change in hearing.Results: The OtoID had a test sensitivity of 80.6% and specificity of 85.3%. A logistic regression model analysis of the probability of an ASHA shift identified by the automated OtoID was conducted. Separate models were fit to establish effects of age, average baseline thresholds in the sensitive range for ototoxicity (SRO), and dose of cisplatin on the probability of a positive hearing change result. Interactions were also included to evaluate these effects on the sensitivity and false-positive rates of the automated test. Results indicated no statistically significant effects of age, of baseline hearing in the SRO frequencies, or of cisplatin dose.Conclusions: The OtoID automated test can be recommended for use. The automated test provides significant personnel efficiencies. The modem with simple text messaging function recently added to the device improves on these efficiencies.