Regio- and Diastereoselective Nickel-Catalyzed Cycloaddition of Activated Cyclopropanes with Allenes
Regio- and Diastereoselective Nickel-Catalyzed Cycloaddition of Activated Cyclopropanes with Allenes
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DOI：
10.1055/s-0034-1378371
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发表时间：
2014-08
期刊：
影响因子：
2
通讯作者：
Rihoko Tombe;T. Iwamoto;T. Kurahashi;S. Matsubara
中科院分区：
文献类型：
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作者：
Rihoko Tombe;T. Iwamoto;T. Kurahashi;S. Matsubara
摘要本文报道了镍催化的活化环丙烷与联烯的分子间[3+2]环加成反应。这种转化在温和的反应条件下产生具有良好的区域和非对映选择性的高度取代的五元碳环化合物。该反应可以推广到各种各样的联烯，以获得相应的加合物。
Abstract Nickel-catalyzed intermolecular [3+2] cycloaddition of activated cyclopropanes with allenes has been developed. This transformation generates highly substituted five-membered carbocyclic compounds with good regio- and diastereoselectivity under mild reaction conditions. This reaction can be extended to a broad variety of allenes to obtain the corresponding adducts.