Rapid Evidence Assessment of the Literature (REAL(©)): streamlining the systematic review process and creating utility for evidence-based health care.
Rapid Evidence Assessment of the Literature (REAL(©)): streamlining the systematic review process and creating utility for evidence-based health care.
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DOI：
10.1186/s13104-015-1604-z
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发表时间：
2015-11-02
影响因子：
1.8
通讯作者：
Jonas, Wayne
中科院分区：
文献类型：
--
作者：
Crawford, Cindy;Boyd, Courtney;Jonas, Wayne
背景：系统评价(SRS)被广泛认为是综合临床研究的最佳手段。然而，传统的方法可能既昂贵又耗时，并可能受到选择和判断偏差的影响。为了做出研究建议、临床或政策决定或实践指南，以有意义的方式解释SR的结果也可能是困难的。Samueli研究所开发了文献快速证据评估(REAL)SR流程来解决这些问题。REAL以简化、高效和可靠的方式提供有关医疗实践、产品或计划的最新、严格、高质量的SR信息。这一过程是由Samueli研究所开发的卫生保健索赔的科学评估和审查(SEARCH)计划的一个组成部分，该计划旨在回答“什么是有效的？”方法/设计：实际过程(1)针对与不同利益攸关方共同开发的特定和相关研究问题定制标准化搜索策略，以调查现有文献；(2)使用结构化工具和规则手册评估文献的数量和质量，以确保以独立方式和；(3)从训练有素的主题专家那里获得正式的、平衡的关于证据对未来研究和当前实践的影响的意见。结果：审查的每个步骤都使用在线工具和质量保证流程，以确保快速、严格、可靠、透明和可重复的SR过程。结论：REAL是一种快速SR过程，旨在简化和帮助对医疗保健索赔进行严格和可靠的评估和审查，以便做出基于证据的知情决策，并已被各种组织使用，旨在洞察医疗保健中“什么是有效的”。使用真实的系统可以促进对政策、资金和研究中适当的下一步的建议，并以及时、透明和具有成本效益的方式做出临床和现场决策。
BACKGROUND: Systematic reviews (SRs) are widely recognized as the best means of synthesizing clinical research. However, traditional approaches can be costly and time-consuming and can be subject to selection and judgment bias. It can also be difficult to interpret the results of a SR in a meaningful way in order to make research recommendations, clinical or policy decisions, or practice guidelines. Samueli Institute has developed the Rapid Evidence Assessment of the Literature (REAL) SR process to address these issues. REAL provides up-to-date, rigorous, high quality SR information on health care practices, products, or programs in a streamlined, efficient and reliable manner. This process is a component of the Scientific Evaluation and Review of Claims in Health Care (SEaRCH) program developed by Samueli Institute, which aims at answering the question of "What works?" in health care.METHODS/DESIGN: The REAL process (1) tailors a standardized search strategy to a specific and relevant research question developed with various stakeholders to survey the available literature; (2) evaluates the quantity and quality of the literature using structured tools and rulebooks to ensure objectivity, reliability and reproducibility of reviewer ratings in an independent fashion and; (3) obtains formalized, balanced input from trained subject matter experts on the implications of the evidence for future research and current practice.RESULTS: Online tools and quality assurance processes are utilized for each step of the review to ensure a rapid, rigorous, reliable, transparent and reproducible SR process.CONCLUSIONS: The REAL is a rapid SR process developed to streamline and aid in the rigorous and reliable evaluation and review of claims in health care in order to make evidence-based, informed decisions, and has been used by a variety of organizations aiming to gain insight into "what works" in health care. Using the REAL system allows for the facilitation of recommendations on appropriate next steps in policy, funding, and research and for making clinical and field decisions in a timely, transparent, and cost-effective manner.