Infection and death from influenza A H1N1 virus in Mexico: a retrospective analysis
Infection and death from influenza A H1N1 virus in Mexico: a retrospective analysis
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DOI：
10.1016/s0140-6736(09)61638-x
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发表时间：
2009-12-01
期刊：
影响因子：
168.9
通讯作者：
Hugo Borja-Aburto, Victor
中科院分区：
文献类型：
--
作者：
Echevarria-Zuno, Santiago;Manuel Mejia-Arangure, Juan;Hugo Borja-Aburto, Victor
背景2009年4月，墨西哥登记了第一例甲型H1N1流感病例，并导致了意外的死亡人数。我们报告的时间和传播的H1N1的情况下，并探讨保护和感染的风险因素，严重的疾病，和death.Methods我们分析了收集的信息，从2009年4月28日至7月31日，流感监测系统，流感样疾病的患者谁出席了诊所的一部分，墨西哥社会保障网络研究所。我们根据人口统计学特征、临床症状、季节性流感疫苗接种状态和从症状发作到入院的时间，计算比值比（OR），以比较门诊就诊时流感样疾病患者H1N1检测阳性的风险、实验室确诊的H1N1病例入院的风险以及住院患者死亡的风险。报告流感样疾病63479例;确诊H1N1病例6945例（11%），门诊患者6407例（92%），入院并存活475例（7%），63例（
Background in April, 2009, the first cases of influenza A H1N1 were registered in Mexico and associated with an unexpected number of deaths. We report the timing and spread of H1N1 in cases, and explore protective and risk factors for infection, severe disease, and death.Methods We analysed information gathered by the influenza surveillance system from April 28 to July 31, 2009, for patients with influenza-like illness who attended clinics that were part of the Mexican Institute for Social Security network. We calculated odds ratios (ORs) to compare risks of testing positive for H1N1 in those with influenza-like illness at clinic visits, the risk of admission for laboratory-confirmed cases of H1N1, and of death for inpatients according to demographic characteristics, clinical symptoms, seasonal influenza vaccine status, and elapsed time from symptom onset to admission.Findings By July 31, 63 479 cases of influenza-like illness were reported; 6945 (11%) cases of H1N1 were confirmed, 6407 (92%) were outpatients, 475 (7%) were admitted and survived, and 63 (