CD34 stem cell stories and lessons from the CD34 wars: the Landsteiner Lecture 2009.

CD34 stem cell stories and lessons from the CD34 wars: the Landsteiner Lecture 2009.
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CD34 干细胞的故事和 CD34 战争的教训:2009 年兰德斯坦纳讲座。

DOI:
10.1111/j.1537-2995.2010.02729.x
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发表时间:
2010
期刊:
影响因子:
2.9
通讯作者:
Civin,CurtI
Civin,CurtI
中科院分区:
医学3区
文献类型:
--
作者:
Civin,CurtI

文献摘要

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本文就CD34干细胞的研究进展及其在临床研究、诊断和治疗中的应用作一综述。他还将这些CD34的发展经验应用于当前与人类胚胎干细胞(HES)细胞和诱导多能干细胞(iPS)细胞相关的问题。他说,在1982年对MoAb和CD34进行研究之后,人们利用CD34和现有的MoAb进行了几项研究,以追踪所有血液谱系的发展。
In this article, the author reviews several developments related to CD34 stem cell and its applications in the current clinical research, diagnosis, and treatment. He also applies lessons from these CD34 developments to current issues related to human embryonic stem (HES) cells and induced pluripotent stem (iPS) cells. He states after his research on MoAb and CD34 in 1982 several studies were conducted by using CD34 with existing MoAbs to trace the development of all the lineages of blood.