Effects of familiarity on child brain networks when listening to a storybook reading: A magneto-encephalographic study
Effects of familiarity on child brain networks when listening to a storybook reading: A magneto-encephalographic study
复制标题
听故事书时熟悉程度对儿童大脑网络的影响：脑磁图研究
DOI：
10.1016/j.neuroimage.2021.118389
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发表时间：
2021
期刊：
影响因子：
5.7
通讯作者：
Kikuchi Mitsuru
中科院分区：
文献类型：
--
作者：
Hasegawa Chiaki;Takahashi Tetsuya;Ikeda Takashi;Yoshimura Yuko;Hiraishi Hirotoshi;Nobukawa Sou;Saito Daisuke N.;Kumazaki Hirokazu;Yaoi Ken;Hirata Masayuki;Asada Minoru;Kikuchi Mitsuru
亲子图书阅读对促进幼儿各种终身认知和社会能力的发展具有重要意义。尽管有许多报道描述了熟悉度对儿童共享阅读的影响，但功能网络结构的确切神经基础仍然不清楚。我们使用图论进行了磁脑图（MEG）实验，以阐明熟悉度在儿童大脑网络中共享阅读中的作用，并测量儿童在听故事书阅读（LSBR）时的连接动态，这代表了儿童和护理人员之间共享书籍阅读的日常活动。LSBR任务是在两种条件下对正常发育的学龄前和学龄儿童（N= 15）进行的：由他们自己的母亲（熟悉条件）与实验者（不熟悉条件）进行阅读。我们使用相位滞后指数（PLI），它捕捉MEG信号的同步，估计功能连接。对于整个大脑网络拓扑结构，使用68个大脑区域作为节点和区域间PLI值作为5个频带的边来产生无向加权图。行为数据（即，注意力和面部表情的程度）通过两种情况下儿童面部的视频图像进行评估。我们的研究结果表明，在母亲的条件下，增强了广泛的功能连接的α带。在母亲的条件下，整个大脑网络的α带表现出地形高度的局部隔离与高度的全球整合，表明增加了小世界的属性。行为分析的结果表明，儿童更专注，并表现出更多的积极的面部表情在母亲的条件下比在实验条件。行为数据显着相关的图形指标在母亲的条件下，但不是在实验条件。在这项研究中，我们确定了LSBR期间儿童大脑连接动力学中熟悉效应的神经相关性。此外，这些与熟悉相关的大脑动力学与孩子的行为密切相关。应用于脑磁图数据的图论可以提供有用的洞察熟悉相关的儿童大脑反应在自然的设置和儿童的态度。
Parent-child book reading is important for fostering the development of various lifelong cognitive and social abilities in young children. Despite numerous reports describing the effects of familiarity on shared reading for children, the exact neural basis of the functional network architecture remains unclear. We conducted Magnet-Encephalographic (MEG) experiments using graph theory to elucidate the role of familiarity in shared reading in a child's brain network and to measure the connectivity dynamics of a child while Listening to Storybook Reading (LSBR), which represents the daily activity of shared book reading between the child and caregiver. The LSBR task was performed with normally developing preschool- and school-age children (N= 15) under two conditions: reading by their own mother (familiar condition) vs. an experimenter (unfamiliar condition). We used the phase lag index (PLI), which captures synchronization of MEG signals, to estimate functional connectivity. For the whole brain network topology, an undirected weighted graph was produced using 68 brain regions as nodes and interregional PLI values as edges for five frequency bands. Behavioral data (i.e., the degree of attention and facial expressions) were evaluated from video images of the child's face during the two conditions. Our results showed enhanced widespread functional connectivity in the alpha band during the mother condition. In the mother condition, the whole brain network in the alpha band exhibited topographically high local segregation with high global integration, indicating an increased small-world property. Results of the behavioral analysis revealed that children were more attentive and showed more positive facial expressions in the mother condition than in the experimenter condition. Behavioral data were significantly correlated with graph metrics in the mother condition but not in the experimenter condition. In this study, we identified the neural correlates of a familiarity effect in children's brain connectivity dynamics during LSBR. Furthermore, these familiarity-related brain dynamics were closely linked to the child's behavior. Graph theory applied to MEG data may provide useful insight into the familiarity-related child brain response in a naturalistic setting and its relevance to child attitudes.