First-trimester Down syndrome screening: pregnant women's knowledge
First-trimester Down syndrome screening: pregnant women's knowledge
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DOI：
10.1002/uog.8839
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发表时间：
2011-08-01
影响因子：
7.1
通讯作者：
Kesmodel, U. S.
中科院分区：
文献类型：
--
作者：
Dahl, K.;Hvidman, L.;Kesmodel, U. S.
目的本研究的主要目的是在知情同意的情况下评估孕妇对妊娠早期唐氏综合征联合筛查的知晓情况。作为第二个目标，我们希望确定孕妇亚群之间相关知识水平的差异，包括那些对产前检查了解不同方式的孕妇。方法数据来源于基于人群的横断面问卷研究，包括15个评估筛查不同方面知识的多项选择题。包括来自丹麦三个产科部门的6427名早期妊娠妇女，免费提供产前筛查。筛查计划的参与者和非参与者都包括在内。结果基于4,095名应答者(%)。亚组间差异采用卡方检验和Logistic回归分析。结果大多数参与者(87.6(86.6-88.6)%至92.6(91.7-93.3)%)正确识别了测试概念和主要筛查条件。更少的参与者(16.4(15.3-17.6)%到43.3(41.8-44.8)%)正确地认识到测试的准确性和除唐氏综合症以外的不良结果的潜在风险。知识水平与受教育年限(调整OR1.0(0.8-1.4)至3.9(2.4-6.4))和参加筛查计划(调整OR0.9(0.6-1.3)至5.9(3.9-8.8))呈正相关。参加个人信息会与更多知识的相关性较弱。结论大多数孕妇正确地识别了检测的概念和主要筛查条件。研究发现，孕妇对测试的准确性和缺陷知之甚少。版权所有(C)2011 ISUOG。作者：John Wiley&Sons，Ltd.
Objectives The primary aim of this study was to assess pregnant women's knowledge of first-trimester combined Down syndrome screening in a setting of required informed consent. As the secondary aim, we wanted to identify relevant differences in knowledge level among subgroups of pregnant women, including those informed in different ways about prenatal examinations.Methods Data stem from a population-based cross-sectional questionnaire study including 15 multiple-choice questions assessing knowledge of different aspects of screening. Included were 6427 first-trimester pregnant women from three Danish obstetric departments offering prenatal screening free of charge. Both participants and non-participants in the screening program were included. The results are based on 4095 responders (64%). Differences between subgroups were examined using chi-squared tests and logistic regression analysis. Estimates are stated with 95% CI.Results The majority of the participants (87.6 (86.6-88.6)% to 92.6 (91.7-93.3)%) correctly identified the test concept and the main condition being screened for. Fewer participants (16.4 (15.3-17.6)% to 43.3 (41.8-44.8)%) correctly recognized test accuracy and the potential risk of adverse findings other than Down syndrome. Knowledge level was positively associated with length of education (adjusted ORs 1.0 (0.8-1.4) to 3.9 (2.4-6.4)) and participation in the screening program (adjusted OR 0.9 (0.6-1.3) to 5.9 (3.9-8.8)). Participation in an individual information session was weakly associated with more knowledge.Conclusion The majority of the pregnant women correctly identified the test concept and the main condition being screened for. The pregnant women were found less knowledgeable on test accuracy and drawbacks. Copyright (C) 2011 ISUOG. Published by John Wiley & Sons, Ltd.