Control of persistent hemiballismus by chronic thalamic stimulation. Report of two cases.
Control of persistent hemiballismus by chronic thalamic stimulation. Report of two cases.
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通过慢性丘脑刺激控制持续性偏侧运动。
DOI：
10.3171/jns.1995.82.3.0501
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发表时间：
1995
影响因子：
4.1
通讯作者：
Takamitsu Yamamoto
中科院分区：
文献类型：
--
作者：
T. Tsubokawa;Y. Katayama;Takamitsu Yamamoto
中风后的持续性偏侧弹道障碍通常很难治疗。弹道运动有时非常剧烈，导致进行性衰竭。作者报告了两个这样的病例，这是成功地治疗慢性丘脑刺激。这些患者中负责弹道运动的病变分别位于丘脑底核和壳核附近。丘脑腹外侧核和腹中间核在白天用0.2至0.3毫秒的脉冲以50至150 Hz和4至7 V连续刺激。几周后，在刺激期间实现了对偏侧震颤的完全控制。这种改善显然不是由于自发恢复，因为刺激终止后弹道运动再次出现。在这两种情况下，刺激保持有效超过16个月，没有任何严重并发症。慢性丘脑刺激似乎是有用的控制持续偏身震颤，因为它是其他不自主运动障碍。
Persistent hemiballismus after stroke is often difficult to treat. The ballistic movement is sometimes so violent that progressive exhaustion results. The authors report two such cases, which were successfully treated by chronic thalamic stimulation. The lesions responsible for the ballistic movement in these patients were located near the subthalamic nucleus and in the putamen, respectively. The thalamic nucleus ventrolateralis and nucleus ventralis intermedius were stimulated with 0.2 to 0.3 msec pulses at 50 to 150 Hz and 4 to 7 V continuously during the day. Several weeks later, complete control of the hemiballismus was achieved during stimulation. The improvement was clearly not attributable to spontaneous recovery, because ballistic movement reappeared after termination of the stimulation. The stimulation has remained effective for more than 16 months in both cases without any serious complications. Chronic thalamic stimulation appears to be useful for controlling persistent hemiballismus, as it is for other involuntary movement disorders.