Sweet DREAMs for Hippo
Sweet DREAMs for Hippo
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DOI:
10.1101/gad.2050411
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发表时间:
2011-05-01
影响因子:
10.5
通讯作者:
Mymryk, Joe S.
中科院分区:
文献类型:
--
作者:
Dick, Frederick A.;Mymryk, Joe S.
The Hippo pathway coordinates organ size and cell proliferation. The retinoblastoma family of proteins regulates progression through the G0/G1 phase of the cell cycle. Disruption of either pathway contributes to cancer formation. Three recent studies in Genes & Development reveal how cellular proliferation is coordinated between these pathways. Here we discuss the implications of these studies and the new questions that they raise.