The peaked audiometric configuration in Meniere's disease: disease related?
The peaked audiometric configuration in Meniere's disease: disease related?
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梅尼埃病的峰值听力配置：与疾病相关吗？
DOI：
10.1044/jslhr.4204.829
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
Schlauch,RS
中科院分区：
文献类型：
--
作者：
Ries,DT;Rickert,M;Schlauch,RS
对3个不同患者组的听力图进行回顾性分析。这3组是（1）单侧梅尼埃病患者，（2）单侧听神经瘤患者，以及（3）来自大型医疗中心听力学诊所的一般临床人群的患者。正如Paparella、McDermott、Luiz和de Sousa（1982）所报道的，梅尼埃病组最常见的测听配置是峰值，在这种情况下，低频和高频的听力都较差，在1.0或2.0 kHz处出现一个听力灵敏度较好的岛。梅尼埃病组中的一些峰值听力图可能是梅尼埃病引起的低频听力损失与由于衰老或其他环境因素引起的高频听力损失相结合的结果。而27%（13/48）的梅尼埃病耳听力图峰值出现在非病耳的高频。因此，峰值听力配置与梅尼埃病相关，如实验诱导的内淋巴积水动物的研究结果所示。在大约9%的一般临床人群和12.5%的听肿瘤患者的耳朵中也观察到峰值听力配置。一个规则的基础上的听力配置，最大限度地识别梅尼埃病患者使用一般临床人群作为对照，并没有以及当肿瘤组作为对照。这一发现提供了进一步的证据，峰值听力图，虽然常见于梅尼埃病，是不是这种疾病的特征。此外，这些结果表明，梅尼埃病的诊断听力配置文件是危险的，在最好的。
A retrospective analysis of audiograms was completed for persons from 3 different patient groups. These 3 groups were (1) persons with unilateral Meniere's disease, (2) persons with unilateral acoustic tumor, and (3) persons from the general clinical population of an audiology clinic in a major medical center. As Paparella, McDermott, Luiz, and de Sousa (1982) also report, the most common audiometric configuration in the Meniere's disease group waspeaked, a condition in which poorer hearing is reported in the low and high frequencies, and an island of better hearing sensitivity occurs at either 1.0 or 2.0 kHz. Some of the peaked audiograms from persons in our Meniere's disease group could be a result of a low-frequency hearing loss caused by Meniere's disease combined with a high-frequency hearing loss due to aging or other environmental factors. However, 27% (13/48) of the peaked audiograms in ears with Meniere's disease were found in persons with no hearing loss in the high frequencies of their nondiseased ear. Thus, the peaked audiometric configuration is associated with Meniere's disease, as suggested by research results from animals with experimentally induced endolymphatic hydrops. Peaked audiometric configurations were also observed in roughly 9% of the general clinical population and in 12.5% of ears of persons with acoustic tumors. A rule—based on the audiometric configurations that maximized identification of patients with Meniere's disease—using the general clinical population as a control did not fare as well when the tumor group was used as a control. This finding provides further evidence that peaked audiograms, although common to Meniere's disease, are not pathognomonic of this disease. Furthermore, these results indicate that the diagnosis of Meniere's disease from audiometric profiles is risky, at best.