UKRI MRC National Musculoskeletal Ageing Network: strategic prioritisation to increase healthy lifespan and minimise physical frailty.

UKRI MRC National Musculoskeletal Ageing Network: strategic prioritisation to increase healthy lifespan and minimise physical frailty.
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UKRI MRC 国家肌肉骨骼衰老网络:战略重点是延长健康寿命并尽量减少身体虚弱。

DOI:
10.1007/s11657-022-01172-z
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发表时间:
2022
影响因子:
3
通讯作者:
Harvey NC
Harvey NC
中科院分区:
医学4区
文献类型:
--
作者:
Harvey NC

文献摘要

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UKRI医学研究理事会国家肌肉骨骼老化网络(主任:Cyrus库珀教授和副主任:尼古拉斯哈维教授)汇集了,在2年的时间里,关键UKRI MRC在肌肉骨骼研究的投资:MRC生命过程流行病学中心,MRC-Versus关节炎肌肉骨骼老化综合研究中心(CIMA),MRC-Versus关节炎肌肉骨骼老化研究中心(CMAR),MRC流行病学股、MRC综合流行病学股和MRC终身健康和老龄化股。总之,这些跨越了南安普顿、谢菲尔德、利物浦、纽卡斯尔、诺丁汉、伯明翰、牛津、布里斯托、剑桥和伦敦大学学院的大学,并与相关的NIHR生物医学研究中心有进一步的联系。这种多学科合作将支持肌肉骨骼老化研究能力和战略的一步变化(主要是在骨质疏松症、骨关节炎、肌肉减少症和类风湿性关节炎等疾病方面),确定关键的易处理的研究优先事项;发展综合的多学科和多样化的技术伙伴关系,以解决已确定的研究差距;提供一个传播最佳实践的平台;支持早期和中期职业研究人员建立研究能力和发展技术专长,以确保目前UKRI投资的寿命;执行从发现科学到临床影响的持续创新研究计划。在这篇社论中,我们简要阐述了对当前形势的看法,并确定了实现健康肌肉骨骼衰老的基础研究重点,正如在英国伦敦医学科学院举行的网络范围研讨会上所阐述和商定的那样,2022年6月17日。
The UKRI Medical Research Council National Musculoskeletal Ageing Network (Director: Professor Cyrus Cooper and Deputy-Director: Professor Nicholas Harvey) brings together, over a 2-year period, key UKRI MRC investments in musculoskeletal research: the MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated Research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together, these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge, and UCL, with further links to associated NIHR Biomedical Research Centres. This multidisciplinary collaboration will underpin a step change in musculoskeletal ageing research capacity and strategy (principally across the diseases osteoporosis, osteoarthritis, sarcopenia, and rheumatoid arthritis) by identifying key tractable research priorities; developing an integrated multidisciplinary and diversified technology partnership to address the identified research gaps; providing a platform to disseminate best practice; supporting early and mid-career researchers to build research capacity and develop technical expertise to ensure longevity to current UKRI investments; prosecuting an ongoing programme of innovative studies from discovery science to clinical impact. In this editorial, we briefly set out perspectives on the current landscape and identify research priorities fundamental to achieving healthy musculoskeletal ageing, as articulated and agreed at a scoping workshop of the Network held at the Academy of Medical Sciences, London, UK, on June 17, 2022.